Best Online TRT Clinic

There’s no avoiding a drop in testosterone production as you age. Maybe you feel it in the gym or the bedroom, or maybe you just find the basic things in life have gotten harder, but you can’t say why. After 40, men lose an average of 1% of their testosterone production each year. Some men do nothing about it.1 Others seek interventions, which might take the form of increased exercise, nutritional supplements, or testosterone replacement therapy (TRT).

Before telemedicine entered the frame, you had to see a urologist or endocrinologist in person to get a prescription for TRT, but now you don’t even have to put pants on. Online TRT clinics can send you an at-home testosterone testing kit (you may have to put pants on to send it back), process your results, provide you with a medical consultation and prescription, and then ship your medication directly to you.

It’s undeniably convenient, but there are a lot of surprising caveats, from significant differences in medication availability across clinics to the quality and ease of testing. In this guide, we’ll break down all the nuances of the top online TRT clinics, so you can decide which approach best suits your needs.

Read on for that comprehensive breakdown, or, if you're pressed for time, check out this handy summary of recommendations:

At Innerbody Research, we comprehensively evaluate every product and service we recommend, including the various TRT clinics in this guide. Our investigation into testosterone and its role in men’s health is so significant that we eventually formulated and produced our own testosterone support supplement, which we’ll detail later in this piece. All told, we’ve spent thousands of hours reading scientific articles pertaining to testosterone and men’s health, and we’ve looked into every company and product on the market offering both prescription and nonprescription interventions.

We built on our vast foundation of knowledge and submitted ourselves to medical intakes and testing from the top TRT clinics in the world, culminating in this breakdown of the best providers of traditional TRT and other testosterone-supporting care. Additionally, like all health-related content on this website, this guide was thoroughly vetted by one or more members of our Medical Review Board for accuracy and will continue to be monitored for updates by our editorial team.

Over the past two decades, Innerbody Research has helped tens of millions of readers make more informed decisions about staying healthy and living healthier lifestyles.

In evaluating online TRT clinics, our team employed a set of five criteria that should be the top considerations for any man seeking testosterone treatment: testing quality, medication options, safety, cost, and convenience. For some men, certain criteria will present specific roadblocks or opportunities that clearly make one company their best choice. Others may need to synthesize info from across these five criteria to find their fit.

Let’s look at each criterion to see which companies fared the best:

Testing quality

Advantage: Maximus Tribe

Testosterone care always begins with testing.2 Before you can be evaluated for a specific testosterone treatment, it’s vital to see that you have low testosterone in the first place. If testing proves that you do, there are other health markers to keep an eye on throughout treatment, which this round of testing should also provide as a baseline.

Central to a diagnosis of low testosterone is your measure of total circulating testosterone.3 Here are some helpful reference ranges, measured in nanograms of testosterone per deciliter of blood (ng/dL):

• Low testosterone: ≤300ng/dL
• Normal testosterone: 300-1,000ng/dL
• High testosterone: ≥1,000ng/dL

A good testosterone test will also measure other critical biomarkers that can either expand your understanding of your testosterone status, point to alternative diagnoses, or serve as safety markers throughout treatment. These other markers include:

• Free testosterone
• Luteinizing hormone (LH)
• Sex hormone-binding globulin (SHBG)
• Vitamin D
• Follicle-stimulating hormone (FSH)
• Estradiol
• Total prostate-specific antigen (PSA)
• Alanine aminotransferase

There are some additional markers available on advanced tests, but these are the core of what you should look for at the outset of treatment, and each one is available on the basic testosterone test from Maximus Tribe. Here’s how that compares to tests from close competitors:

As you can see, Maximus Tribe offers the test with the most biomarkers checked for an at-home experience. The only two tests with more biomarkers require you to visit a lab in person and have blood drawn from a vein. Maximus’ pain-free blood draw and low price for an at-home test make it the top pick in a competitive market.

Medication options

Advantage: Hone Health

Having more than one or two avenues to explore for testosterone replacement is critical. Different medications have varying degrees of efficacy, onset, and adverse effect risk, so being able to switch from one to another if you hit a roadblock — without having to switch companies — is extremely convenient and helps ensure better continuity of care.

Hone Health stands out among providers for offering a handful of options for more traditional TRT to increase testosterone levels directly alongside both clomiphene and enclomiphene for an indirect approach that can preserve fertility.

Here’s a look at how Hone compares to competitors:

Hone is tied with Alyn for having the largest offering, but Hone delivers its oral testosterone in a more convenient and bioavailable oral lozenge compared to Alyn’s more typical pill. That’s just enough to give it the edge in our ranking here.

Safety

Advantage: 1st Optimal

Treatment variety, which we just touched on, certainly plays a role in safety. Specifically, we regard it as an added layer of safety to have access to both direct and indirect TRT medications, the latter of which typically have better side effect profiles in exchange for a slower onset of effects.

Testing quality is also a major component of safety, as having the right biomarkers tested can help ensure that the medication is not only working properly, but that well-known potential side effects aren’t occurring. For example, the doctor we spoke with at 1st Optimal explained that enclomiphene can, in certain cases, elevate estradiol to unhealthy levels that could counteract some of its intended effects. So having an estradiol biomarker on your baseline and follow-up tests can improve safety and prevent hormonal imbalances.

But what sets 1st Optimal apart for safety in our minds are two additional factors:

1. Live consultation with an MD prior to prescription
2. Available follow-up testing to identify specific adverse effects

To the first point, nearly every other provider we investigated would give you a prescription after either a simple medical questionnaire or a consultation with a nurse practitioner (NP) or physician assistant (PA). But 1st Optimal has you sit down for a Zoom call with a medical doctor before granting your prescription. Not to disparage NPs and PAs, which are both noteworthy professions, but 1st Optimal’s added layer of review from someone at the top of their field is something you rarely see in telemedicine.

To the second point, 1st Optimal has a suite of various follow-up tests it can employ if you present with certain symptoms. These can help determine whether, say, a gut problem that crops up during treatment is related to your medication. That way, you can take steps to address those symptoms from an informed place, rather than just discontinuing or switching medications and hoping for the best.

Cost

Advantage: Maximus Tribe

Online TRT clinics typically charge for products and services in two ways. Some offer everything à la carte, allowing you to pay for testing and medication as you go. Others employ membership fees that sometimes include testing or medication, and other times do not. When those fees don’t cover testing or medication, you usually end up paying à la carte, but at lower prices than you see from companies that don’t charge for membership.

Maximus Tribe does not charge for membership, yet it maintains some of the lowest prices for testing and medication we’ve seen, making it an economical outlier that still offers top-tier products and services to its customers. That includes a $99 at-home test and medication costs as low as $99/month.

Here’s a look at what one year of enclomiphene treatment with quarterly retesting would cost from five of the top companies in this guide:

But wait — that Hims price is lower, isn’t it? Well, for enclomiphene, it is, but there are two caveats. First is that enclomiphene is the only testosterone treatment offered through Hims at this time. Maximus offers nearly identical prices on more options. Second is that Maximus’ $99/month cost is for a 12-month subscription, while Hims’ $99 price point is for a 10-month subscription.

That difference is a double-edged sword. On the one hand, you’ll pay less going through Hims for the long haul — think decades, not years. On the other hand, that first year with Hims will incur $1,980 in charges. If your plan is to try enclomiphene for a year, then retest and reevaluate with your doctor, you’ll pay less with Maximus.

Ultimately, that makes this nuanced cost comparison come down to personal preference, but the larger set of well-priced available treatments from Maximus gives it the advantage over Hims.

Convenience

Advantage: Maximus Tribe

While the safety measures from 1st Optimal are laudable, they can slow things down. Specifically, having an intake appointment on one day, only to have to attend a follow-up appointment with an MD before getting a prescription, is a little arduous in the telehealth age. Most other companies, Maximus Tribe included, are content to have you fill out a questionnaire, take an at-home blood test, and receive your prescription after a brief message exchange on the company’s dedicated user platform.

Several online TRT clinics we’ve scrutinized also have underdeveloped websites that sometimes feel designed to leave you with more questions than answers, likely so that you have to book an appointment to get to the information you want. Maximus’ website does quite the opposite, spelling out its offerings clearly, right down to pricing.

Maximus also employs a painless shoulder-mounted blood-draw method for at-home testing — Tasso+ — that’s so effective at minimizing the discomfort that our testers weren’t sure they’d applied it properly until they saw blood begin to flow.

Together, these attributes give Maximus a clear victory for convenience over its competitors.

Online testosterone replacement therapy (TRT) clinics are telehealth providers offering all the steps involved in acquiring a prescription and medication for testosterone replacement on a single website. These companies handle:

• Initial testosterone level testing
• Connection with an MD, physician assistant (PA), or nurse practitioner (NP)
• Prescriptions for medication when appropriate
• Medication delivery to your home
• Follow-up testing
• Medication adjustment as needed

Having all of these services in one place that you can access from home is undeniably convenient, and it opens up the possibility of seeking medical care for many more men than would otherwise have it.

That said, most of these clinics operate outside of the insurance industry; they don’t take any kind of medical insurance, and everything you pay for comes out of your pocket. Some may provide the means to file a claim for reimbursement through an FSA or HSA, but not all companies do so.

Online TRT clinics offer a variety of medications, with few clinics having identical catalogs to one another. We’ll go a little deeper into how each medication works in the section below this one, but here’s a quick breakdown of the two major classes of medications you're likely to see at an online TRT clinic:

For reference, common forms of direct testosterone replacement include:

• Testosterone cypionate injections
• Testosterone creams and patches
• Oral testosterone pills or lozenges

While indirect means include:

• Clomiphene and enclomiphene citrate
• Anastrozole
• Human chorionic gonadotropin (hCG)

You and your prescriber will discuss which route and medication would be best for your specific needs and risk profile.

To understand what TRT can do for low testosterone, it helps to understand what roles testosterone plays in the first place. The obvious connections between testosterone and masculinity might lead you to the mistaken conclusion that testosterone only serves to grow muscle and body hair, and maybe somehow get involved with fertility.

But testosterone is a much more involved player in male health. You only have to look at the common symptoms of low testosterone as a way to understand how important it is. Those symptoms include:4

Obviously, healthy testosterone levels are correlated directly with numerous aspects of health, including sexual, metabolic, mental, and cardiovascular.

So, by restoring testosterone to healthy levels, these interventions can mitigate a host of symptoms and improve men’s quality of life.

Now that we’ve seen how improving testosterone levels can improve so many aspects of health, we need to understand how each intervention achieves its goal.

Online TRT clinics are suitable for any man looking to diagnose and treat low testosterone. Many of the clinics we’ve dealt with don’t need you to meet the criteria for clinical hypogonadism to receive treatment.

Since men typically lose about 1% of their testosterone every year after age 40, these clinics and many urologists and endocrinologists will consider a man with testosterone levels between 300ng/dL and 400ng/dL to be a candidate, even if clinical deficiency only technically begins below 300ng/dL.1 2 Candidacy is even more likely if your levels are on the low side of normal or below AND you’re experiencing specific effects like low libido, mood problems, or body composition challenges.

These clinics are especially good for men who want to avoid seeing a doctor in person for their concerns. You may not have time to get to a clinic, or you may even feel embarrassed about the issue. Whatever the cause, using a clinic online is undeniably more convenient.

Who might want to look elsewhere?

Men who might want to look elsewhere for TRT or to address their symptoms include those who:

Online TRT clinics themselves are safe in that they’re subject to most of the same oversight applied to in-person medical care. The process to acquire a prescription also involves baseline medical testing reviewed by an MD, PA, or NP, and each company we’ve included in this guide is LegalScript Certified, indicating adherence to stringent legal and safety requirements.

Where safety profiles diverge is in the specific medications available, as each has a particular side effect profile. Having more options is often safer, as it allows you to switch to another medication if you experience side effects.

To that end, let’s look at some of the side effects of common TRT treatments, so you’ll know what to ask about in your consultation:

Best for most men

Maximus Tribe relatively easily earned its ranking as the best option for most men thanks to the diversity of its catalog, its competitive pricing, and its extreme ease of use. Our earliest interactions with the company involved getting our hands on its at-home test to see how it compared to the dozens we’d tried from other companies through the years.

Not only did Maximus’ test cost less than or about as much as other at-home tests on the market, but it also checked more biomarkers, so we were hopeful. The test itself uses a device called Tasso+, a shoulder-mounted blood draw system that is utterly painless. One of our testers nearly wasted his kit because he was tempted to remove the device and check it for a malfunction after he pressed its big red button and felt nothing on his arm. Then the blood began to flow into the vial.

We dropped our samples off at a local FedEx dropbox at around 3 p.m. on a Wednesday, and we had our results by just before 6 p.m. the next day. That’s incredibly fast. The average turnaround for the dozens of at-home tests we’ve tried over the years is closer to a full week. Some tests took several weeks to report back. This was essentially next-day service.

After those results were in, we were quickly messaged by an affiliated MD through Maximus’ portal, and after a brief messaging session, we had our prescriptions filled. Those medications arrived within two days.

For most men, this process is fast, easy, convenient, and safe, with those extra biomarkers serving as crucial safeguards against common treatment-related effects. Once you’ve been through the testing process, you’ll have access to several TRT treatments, including:

• TRT injections
• TRT cream
• Enclomiphene citrate
• Oral testosterone

You can also get hCG alongside your injectable TRT, and you can combine enclomiphene with tadalafil, vardenafil, or both. These are two effective erectile dysfunction (ED) medications that can immediately grant you relief for the erectile and libido issues that are so prevalent among men with low testosterone.26

Maximus Tribe pricing

Unlike many of its competitors, Maximus Tribe doesn’t charge a membership fee. Instead, it offers each of its products à la carte, with monthly, quarterly, and yearly pricing plans, allowing you to stock up on your medications and save a decent amount of money over time.

It’s important to remember that these are treatments you’ll continue to take for as long as you want your testosterone levels to remain normalized. So long-term savings opportunities are definitely welcome in this space.

Here’s a look at the three pricing tiers for Maximus’ most prominent testosterone therapies:

There are other options throughout Maximus’ lineup that combine these therapies for additional discounts, such as a program that supplies you with oral enclomiphene and injectable TRT. But these aren’t likely where most men would start, as monotherapy has a lower risk profile at the outset. Of course, that’s ultimately a discussion for you to have with your intake physician.

Best source for long-term enclomiphene

Hims has long been an outstanding resource for men seeking relief from things like hair loss, ED, and premature ejaculation. It offers prescription and nonprescription products for various issues, and its robust and polished telemed interface is one of the easiest to use in the business.

The company only recently began developing offerings for low testosterone, including enclomiphene citrate prescriptions and an at-home test. That at-home test is fairly impressive, using a shoulder-mounted Tasso+ blood draw like the one Maximus uses and costing just $94. If you qualify for treatment, the $94 is applied to the cost of your medication order. If you don’t qualify, it’s not refunded, but the company gives you a $94 credit to use elsewhere on the site.

Qualifying men will have the option to receive enclomiphene on its own or compounded to include tadalafil in a single pill. Tadalafil is the generic form of Cialis, a daily medication for ED that can help ameliorate that specific symptom of low testosterone within an hour of your first dose.27 It continues working from that first dose for as long as you keep taking it, providing relief much faster than enclomiphene on its own, which takes several weeks to normalize testosterone levels.

According to the site, Hims will soon carry oral and injectable testosterone at some point in 2026, but these medications are unavailable at the time of this writing.

Hims testosterone pricing

Enclomiphene is currently the only treatment available through Hims. If you choose to have your enclomiphene compounded with tadalafil, the price stays the same. You can get your prescription in three-, five-, or ten-month supplies, with that ten-month option delivering the lowest cost for enclomiphene in the shortest interval on the market. You can get a similar price from Maximus Tribe, but only if you opt for a one-year subscription. It’s a little less expensive up front to get started with Hims.

Here’s how that works out:

As you can see, opting for a ten-month supply gets you enclomiphene for less than $100/month, which is as good a price as we’ve seen. And considering the fact that you’ll need to take the medication for as long as you want your testosterone levels to remain high, longer-term prescriptions are a perfectly viable option, so long as you have the money to invest in them.

Most comprehensive medical care

1st Optimal is probably the least polished of all the online clinics in this guide, with a relatively bare-bones website and a very useful but somewhat poorly designed user portal. That said, the company provides what, in our experience, has been some of the most comprehensive medical care in all of telemedicine, not just TRT.

For starters, signing up connects you with a PA who becomes your main point of contact throughout treatment. You can keep in touch via email, the company messaging portal, or (in our case at least) via text. Having this point of contact for quick answers to most questions is invaluable.

But this isn’t the person who ultimately writes your prescription, and that serves as an additional safeguard that many other telehealth outfits lack. Instead, you have to have a live consultation with an MD before getting a prescription. The meeting actually involves you, an MD, and your PA contact, so you get the sense that there’s a team working on your behalf.

There are a lot of options for your treatment, as well, including enclomiphene, injectable and oral testosterone, and testosterone cream. Lab results come with a detailed analysis of your numbers and how they relate to your treatment plan, and follow-up tests are included as part of the program every three months or so.

Also, 1st Optimal offers a suite of other tests that can help nail down the causes of certain potential side effects of medication or ensure you’re a viable candidate if you have certain concerns that the testosterone test itself doesn’t cover.

Taken together, these safety measures and customer care services combine to make 1st Optimal the best place to start if you’re concerned that the telehealth process is a little too remote, and you’d rather have a feeling of great support. The flip side, however, is that this whole process takes a bit longer than with more modern telehealth outfits, like Hims and Maximus Tribe. You’re essentially trading convenience for some additional medical oversight.

1st Optimal pricing

1st Optimal essentially has two membership levels for its TRT offerings. The lower tier gets you your initial labs and access to discounted medication, but the cost of those meds can fluctuate, depending on the pricing of partner pharmacies. A higher tier costs more per month, but it includes all your follow-up labs and your medication at a consistent price, so you know exactly what you’ll be paying month after month.

Here’s how that pricing works out:

It’s possible that, in some months, you’ll end up paying less with Tier 1 than you would with Tier 2, but once you include the cost of testing and account for occasional spikes in medication cost, it becomes clear that Tier 2 is a superior deal.

Most treatment options

Hone Health has been providing online TRT for longer than any other company in this guide. Its offering has changed a bit through the years, but it remains a viable option for men seeking certain treatments, although its membership structure is both confusing and frustrating.

Essentially, if you want access to medication, you need to use the Premium plan, as the Basic plan stops at providing you with biannual labs, paid consultations, and OTC interventions. The bright side is that Hone’s Premium membership grants you access to more medications — or, more accurately, more forms of medications — than competitors. Specifically, you can get:

• TRT injections
• TRT cream
• Oral TRT troches
• Clomiphene citrate
• Enclomiphene citrate
• Anastrozole

That list is about as comprehensive as what you can get from Alyn, but Hone’s prices are much better, and Alyn only offers its oral TRT as a pill and not a lozenge. Administration via troche should result in a faster and more thorough absorption into the bloodstream compared to oral tablets.28 Alyn also doesn’t offer injections at this time, though the company says they’re coming soon.

Hone Health pricing

So, how does that complex membership-to-medication relationship work out for your bottom line? Here’s a quick breakdown of total costs per medication with your membership included:

Add to that a $65 biannual charge for lab testing, and you can see that there are less expensive options spelled out elsewhere in this guide, some of which can cost less than Hone’s membership fee alone. Still, Hone is a good source if you aren’t sure which treatment you want to try but want access to as many options as possible in one place.

Best supplement alternative to TRT

For men interested in improving low testosterone levels without a prescription, there are dozens, if not hundreds, of supplements on the market that claim to do so. We’ve spent nearly a decade writing about them, discussing large and small problems with one or another, until we realized that there was no truly great option out there. That’s when we decided to make our own.

In the ensuing years, other companies have produced some improved testosterone boosters, but Innerbody Labs still boasts the highest doses of a specific combination of ingredients with significant scientific support to boost testosterone.

Specifically, it includes:

• Ashwagandha: 600mg KSM-66
• Fenugreek: 600mg
• Maca: 3,000mg
• Longjack: 400mg
• Vitamin A: 750mcg
• Vitamin D: 1000IU
• Vitamin K2: 75mcg
• Zinc: 25mg citrate
• Copper: 300mcg
• Selenium: 20mcg
• Black pepper extract: 5mg

To be clear, this is a nutritional supplement, not a clinic. Innerbody doesn’t offer lab testing or ongoing medical support. But as a viable alternative to prescription intervention, it’s about as good as you’ll find anywhere.

Here are some highlights from its ingredient bill:

As you continue to go down the list of ingredients, the pattern remains: all components with good human research either to boost testosterone or to support the other ingredients in their efforts to boost testosterone.

And while Innerbody Labs hasn’t had its supplement subjected to its own clinical study yet, the site’s managing editor took it for 12 weeks and more than doubled both his total testosterone and free testosterone.

Innerbody Labs pricing

Innerbody Labs offers its Testosterone Support as a one-time purchase or on a subscription basis, with the option to subscribe to larger order sizes to save even more money. Here’s how it works:

As you can see, you can save up to 40% by selecting a semiannual subscription, not unlike some of the bulk options offered by companies like Hims and Maximus Tribe. Compared to monthly TRT, this is actually less expensive.

Another benefit of going the supplement route is that there's a money-back guarantee involved — not something you see with prescription medication. If you’re unsatisfied with your results after 30 days, you can get a full refund. And all orders in the U.S. ship for free.

Let’s say you go through the trouble of connecting with one of these clinics for a stand-alone testosterone test, or going through your PCP to have your levels checked, and your results come back normal. But you still have symptoms related to low testosterone. Maybe you’re more fatigued than you used to be. Maybe you’re having a hard time gaining muscle or losing fat.

The first and most important step would be to check in with your doctor to rule out other possible causes of these issues. If they come back with something not particularly helpful, like “you’re just getting older,” then you might want to explore some of these alternative approaches: