Best Nitric Oxide Supplements
Want a better pump and a longer workout? Find out if you can achieve these goals and more with today's nitric oxide boosters.
If you're committed to working out, you may be looking for ways to improve endurance, recover faster, and get more out of every training session. There are plenty of pre-workout supplements on the market, but figuring out which ones are actually worth your money can be challenging. One increasingly popular option is a nitric oxide supplement. Research suggests these formulas can enhance exercise performance, support muscle recovery, and even promote healthy blood flow throughout the body.1 27 28
But not all products are created equal. Ingredient quality, dosing, and formulation vary considerably, which is why some are far more effective than others. In this guide, we'll help you identify the nitric oxide supplements that stand out from the rest.
If you don't have time to read the full guide, take a look at our top recommendations below.
Summary of recommendations
- Best overall: Type Zero Clean Stim-Free Pre-Workout
- Best budget pick: Kaged L-Citrulline
- Best beetroot option: HumanN SPORT Pre-Workout
- Best pre-workout: Gorilla Mode Nitric
- Best tasting: Type Zero Clean Stim-Free Pre-Workout
- Best for erectile dysfunction: Nutricost L-Arginine Powder
Type Zero combines clinically relevant doses of nitric oxide and performance ingredients in a clean, naturally flavored formula.
Type Zero makes vegan- and keto-friendly supplements without artificial colors, flavors, or sweeteners. Its blend of citrulline malate, arginine AKG, betaine, and other performance ingredients is designed to increase nitric oxide production, improve blood flow, support stronger workouts, and help you stay focused from your first set to your last.
Shop on TypeZero.com and receive 15% off with code INNERBODY15.
In this Review
Why you should trust us
At Innerbody Research, we extensively test each health service or product we review, including nitric oxide boosters. Our team purchased and tested top products to determine which ones are superior, which ones could benefit specific individuals, and which ones to avoid. That testing experience allows us to relay to you critical information about taste, mixability, shipping, and customer service. We were also able to see how these supplements made us feel and whether they had any effect on our exercise regimen. Our testers aren’t professional athletes or trainers but instead regular folks who intend to get a healthy amount of exercise and eat well.
To bolster our team’s experiences with a deeper understanding of the topic, we devoted nearly 600 hours to studying more than 150 scholarly articles pertaining to fitness and nitric oxide. Additionally, like all health-related content on this website, this review was thoroughly vetted by one or more members of our Medical Review Board for accuracy. We’ll stay on top of any developments in the NO landscape to ensure our recommendations remain current.
Over the past two decades, Innerbody Research has helped tens of millions of readers make more informed decisions about staying healthy and living healthier lifestyles.
How we evaluated nitric oxide supplements
Nitric oxide supplements are used for a variety of reasons, from supporting exercise performance and recovery to promoting healthy blood flow. To identify the best options, we evaluated each product across five key categories:
- Effectiveness
- Safety
- Taste and mixability
- Cost
- Customer service
Effectiveness carried the most weight, with preference given to products that provide clinically relevant doses of well-studied ingredients. Safety was a close second, taking into account potential interactions, side effects, and ingredient transparency. We also considered taste and mixability for powdered supplements, since they're more likely to become part of your routine if they're pleasant to use. Cost helped us identify products that deliver strong value, while convenience factored in things like serving size, dosing flexibility, and refund policies for first-time buyers.
Effectiveness
Advantage: Type Zero Clean Stim-Free Pre-Workout
When we evaluated effectiveness, we looked for formulas that aligned with the ingredients and doses most consistently supported by human research. Most nitric oxide supplements rely on one of three approaches: L-citrulline, L-arginine, or dietary nitrates from ingredients like beetroot. These remain the strongest-supported ways to increase nitric oxide availability, improve blood flow, and support exercise performance.2
What ultimately set Type Zero apart wasn't that it contained one exceptional ingredient — it was that it combined two of the best-studied nitric oxide precursors with several well-supported performance ingredients in a thoughtfully balanced formula. It provides:
- 5g of citrulline malate and 2g of arginine AKG, two ingredients that support nitric oxide production through complementary pathways20
- 1.5g of betaine, an ingredient with evidence for improving exercise performance while also helping maintain healthy homocysteine levels, an amino acid associated with cardiovascular risk when elevated12
- 1g of beta-alanine, a well-studied performance ingredient that may help improve high-intensity exercise performance53
- 150mg of Alpha GPC and 500mg of N-acetyl L-tyrosine, two ingredients commonly included to support focus during training54 55
- A completely transparent label, with no proprietary blends or hidden dosages, making it easy to compare the formula against what's actually been studied.
We also appreciated what Type Zero doesn't include. Many nitric oxide formulas rely on stimulants to make workouts feel more effective. Type Zero instead lets the nitric oxide ingredients do the heavy lifting, making it an excellent option for evening workouts or anyone who wants better blood flow and performance without caffeine.
Gorilla Mode Nitric came very close to earning this category. In fact, if your only goal is maximizing gym performance, muscle pumps, and training intensity, we'd probably lean toward Gorilla Mode Nitric. It packs in an enormous number of performance ingredients, including creatine, glycerol, taurine, and several nitric oxide boosters, making it one of the most comprehensive pre-workout formulas we reviewed.
Ultimately, though, we felt Type Zero struck the better overall balance. It focuses on the ingredients with the strongest evidence for nitric oxide production while adding several complementary performance ingredients, making it the formula we'd recommend to the widest range of people.
Safety
Advantage: HumanN SPORT Pre-Workout
When evaluating safety, we looked for products that use well-studied ingredients, undergo independent testing, and follow high manufacturing standards. HumanN earned the advantage for several reasons:
- A beetroot-based formula built around one of the best-studied dietary sources of nitrate. Beetroot has been evaluated extensively in human clinical trials and consistently demonstrates a strong safety profile while supporting blood flow, cardiovascular health, and exercise performance.25
- Independent third-party testing verifies its products for contaminants, ingredient identity, and label accuracy.
- Manufacturing in cGMP-certified facilities, which follow FDA quality standards for dietary supplements.
- NSF Certified for Sport, providing additional assurance that it's free of substances banned by major athletic organizations.
Kaged also impressed us with its Informed Sport certification, third-party testing, and straightforward single-ingredient formula, but HumanN ultimately earned the advantage because its beetroot formula has also been evaluated in a randomized, placebo-controlled human clinical trial.26 While Kaged wasn't far behind, HumanN’s additional quality assurance gave it the edge in our safety evaluation.
Regardless of which supplement you choose, it's important to remember that nitric oxide boosters aren't appropriate for everyone. Because they increase nitric oxide availability and relax blood vessels, they can interact with certain medications, particularly nitrates prescribed for chest pain and some blood pressure medications. If you have cardiovascular disease or take prescription medications, it's a good idea to speak with your healthcare provider before starting a nitric oxide supplement.5
Taste and mixability
Advantage: Type Zero
When it comes to taste and mixability, Type Zero earned the edge. As a pre-workout, it's designed to be something you'll actually look forward to drinking, and it succeeds. Its fruity flavors are well-balanced without being overly sweet or artificial, and the powder dissolves easily with minimal clumping. The company also relies primarily on stevia instead of artificial sweeteners, giving it a cleaner finish than many competing pre-workouts.
HumanN SPORT Pre-Workout narrowly missed the top spot. Like Type Zero, it mixes easily into water, with only a small amount of clumping that disappeared after a little extra stirring. It’s unmistakably beet-forward but tempered by cherry notes, creating a flavor that our testers enjoyed much more than they’d expected.
Cost
Advantage: Kaged L-Citrulline
When evaluating value, we considered more than just the sticker price. We also looked at cost per serving, ingredient quality, and independent testing to determine the overall value.
Kaged L-Citrulline stood out by delivering:
- 100 servings for just $15, making it one of the least expensive products in our guide.
- A 20% subscription discount, dropping the price to just $12 with free shipping and no long-term commitment.
- Informed Sport certification and third-party testing for banned substances and heavy metals — a level of quality assurance that's uncommon at this price point.
But if outright affordability is your top priority, Nutricost L-Arginine deserves an honorable mention here. At $14.97 for a one-time purchase (or $11.98 with a subscription), it delivers a full 5g serving at one of the lowest prices we found. But unlike Kaged, Nutricost lacks Informed Sport certification, an important consideration for competitive athletes and anyone who values that extra level of third-party verification.
Convenience
Advantage: HumanN
Convenience extends beyond how easy a supplement is to take. We also considered factors like shipping, subscriptions, return policies, customer support, and the overall purchasing experience.
HumanN earned the advantage for several reasons:
- A generous 90-day money-back guarantee, giving new customers plenty of time to decide whether the product is right for them
- Flexible subscription options that save you up to 24%, include free shipping on every recurring order, and can be adjusted or canceled at any time
- Bundle discounts for customers purchasing multiple canisters, making it easier to stock up while lowering the cost per container
- Multiple customer support options, including live chat and access to product specialists by phone during business hours
Type Zero also performed well in this category. It offers a 60-day money-back guarantee, responsive live chat, and a straightforward purchasing experience, but HumanN ultimately edged it out with its longer guarantee period.
How our top recommendations compare
In order to get a clear sense of how the top nitric oxide boosters compare, we've put together a handy chart. Prices in the chart reflect one-time purchases before any discounts for bulk or subscription programs would apply (prices have been rounded to the nearest cent or dollar).
What is nitric oxide?
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Nitric oxide (NO) is a colorless gas that serves a specialized role in the body as a signaling molecule responsible, in part, for vasodilation.30 This means that it increases blood flow throughout your body by relaxing blood vessel muscles, which lowers blood pressure and can help red blood cells deliver more oxygen. Your body produces nitric oxide from the amino acid L-arginine, and can also generate it from dietary nitrates found in foods like leafy greens and beets.31 Vitamin C and other antioxidants may help support these pathways under certain conditions.32
Nitric oxide production also tends to decline with age and can be impaired by cardiovascular risk factors such as smoking, high cholesterol, diabetes, and physical inactivity. This can cause issues like:
- Poor vision
- Brain fog
- Low energy
- Slow recovery times
- Erectile dysfunction
Eating foods rich in nitrates, exercising regularly, and taking probiotics or antioxidants can help boost nitric oxide levels naturally. Some people opt for nitric oxide supplements, which use various ingredients to increase levels of nitric oxide production.
How do nitric oxide supplements work?
Nitric oxide supplements, or NO boosters, don't actually contain nitric oxide. Instead, they provide ingredients your body uses to produce more of it. Researchers typically evaluate these ingredients by measuring changes in blood pressure, blood flow, exercise performance, muscle recovery, and other markers of nitric oxide activity.29
Popular ingredients in nitric oxide supplements include:
L-Arginine
Thanks to its role in supplements designed to address male sexual dysfunction, L-arginine has undergone a significant amount of research.3 It's one of the best-studied nitric oxide precursors and has demonstrated modest benefits for blood pressure and endothelial function in human studies.21 33 Although a study from 2011 measuring V0₂ max in trained cyclists found that arginine had no meaningful effect, some evidence suggests it may perform better in lesser-trained individuals.1 4 Typical doses in studies range from 1.5g to 25g per day, with effects observed even at the lower end of that range.
L-Citrulline
L-citrulline is often administered alongside or instead of L-arginine because it's converted into L-arginine in the body and raises circulating arginine levels more efficiently.34 Doses around 6g have been common in clinical studies and have produced blood pressure effects comparable to those seen with L-arginine.5 An 8g study involving resistance-trained men also found improvements in workout performance and reduced post-exercise muscle soreness.6 More recent reviews continue to support modest improvements in muscular endurance and recovery, though benefits for aerobic endurance remain mixed.27
Beetroot extract or powder
Beetroot is one of the richest natural dietary sources of nitrate and has become among the best-studied ingredients for increasing nitric oxide production.7 Comparing beetroot supplements can be challenging, as some contain powder, others use concentrated extracts, and many of the clinical studies have evaluated beetroot juice instead. Even so, more recent systematic reviews continue to support modest reductions in blood pressure and small improvements in exercise performance, particularly when supplements provide standardized nitrate doses.8 35
L-Norvaline
L-norvaline hasn't been studied nearly as extensively as L-arginine or L-citrulline, though animal research suggests it may help increase nitric oxide availability by inhibiting arginase, the enzyme that breaks down arginine.9 Unfortunately, L-norvaline is less widely available than other nitric oxide ingredients and is often more expensive. There have also been reports of potential toxicity, though more recent analyses suggest those concerns may have been overstated.10
Betaine
Clinical research involving dialysis patients showed that betaine could help regulate blood pressure, though less dramatically than dedicated nitric oxide precursors.11 Additional research has shown that betaine helps maintain healthy homocysteine levels, an amino acid linked to cardiovascular disease when present at elevated levels.12 It has also been studied for improving exercise performance, making it a useful addition to many nitric oxide formulas.
Pine bark extract
Pine bark extract appears in several nitric oxide supplements because it may help support endothelial function. However, most human studies have evaluated it alongside L-arginine (and sometimes grape seed extract), making it difficult to determine how much benefit pine bark provides on its own.13
Are nitric oxide supplements safe?
For most healthy adults, nitric oxide supplements appear to be well -tolerated when taken as directed. The ingredients with the strongest evidence — L-citrulline, L-arginine, and dietary nitrates from beetroot — have all been evaluated in numerous human clinical trials, where reported side effects are generally mild and most commonly include digestive discomfort, headache, or temporary reductions in blood pressure.29 30 31
The primary safety consideration is their effect on blood pressure. Because nitric oxide relaxes blood vessels, these supplements can enhance the effects of medications that also lower blood pressure. As a result, you should speak with your healthcare provider before taking a nitric oxide supplement if you:2
- Take prescription nitrates for chest pain (such as nitroglycerin)
- Use medications to treat high blood pressure
- Take prescription medications for erectile dysfunction, such as sildenafil or tadalafil
- Have chronically low blood pressure or a history of dizziness or fainting
Many nitric oxide supplements are also marketed as pre-workouts and combine several nitric oxide-supporting ingredients into a single formula. While these combinations are generally considered safe for healthy adults, there's relatively little research evaluating how multiple nitric oxide precursors interact compared to studying each ingredient individually.1 Fortunately, most commercial products provide ingredient doses that fall within — or below — the ranges commonly evaluated in human clinical trials.27
Who are nitric oxide supplements for?
Nitric oxide supplements are best suited for adults looking to improve blood flow, exercise performance, or cardiovascular health. While different ingredients work through different mechanisms, the strongest evidence supports benefits that are generally modest rather than dramatic. They're best viewed as tools to complement a healthy lifestyle, not replace one.1 27 35
More specifically, the following groups stand to benefit most:
People looking to improve workout performance
People with mildly high blood pressure
Several nitric oxide ingredients, particularly beetroot-derived nitrates and L-arginine, have been shown to modestly reduce blood pressure by improving blood vessel function. These supplements aren't a replacement for prescription medication, but they may provide additional support alongside lifestyle changes.8 14 35
Men with mild erectile dysfunction
Nitric oxide plays a critical role in achieving erections by increasing blood flow to penile tissue. While the evidence for supplements is mixed, some studies suggest L-arginine and L-citrulline may improve erectile function, particularly in men with mild ED or when combined with other nitric oxide-supporting ingredients.15 36 44
Recreational athletes
Who are they not for?
Nitric oxide supplements aren't the right fit for everyone. You may want to consider another approach if you fall into one of the following groups:
People expecting dramatic strength or muscle gains
Nitric oxide supplements can improve blood flow, muscular endurance, and recovery, but their effects are generally modest. They shouldn't be viewed as a replacement for progressive training, proper nutrition, or adequate recovery.27
People taking nitrates or certain blood pressure medications
Because nitric oxide supplements can lower blood pressure, combining them with prescription nitrates or some antihypertensive medications may increase the risk of excessive blood pressure reduction. Anyone taking these medications should consult their healthcare provider before using a nitric oxide supplement.5
Men looking for a substitute for prescription ED medication
Although nitric oxide is essential for normal erectile function, supplements don't work like prescription PDE5 inhibitors. Research suggests they may provide modest benefits for some men with mild erectile dysfunction, but they shouldn't be expected to produce the same results as medications like sildenafil or tadalafil.15 36
Type Zero Clean Stim-Free Pre-Workout
Best overall and best tasting
Photo by Innerbody Research
Pros
- High doses of several NO-boosting ingredients
- Vegan- and keto-friendly
- Preferred taste among our testers
- Save 20% with a subscription
- No artificial colors, flavors, or sweeteners
- Take 15% off with promo code INNERBODY15
Cons
- Contains huperzine A, which some experts recommend cycling
- Among the most expensive supplements in our guide on a per-serving basis
- Free shipping requires a $50 minimum purchase
Type Zero doesn’t have as large a catalog as many of its competitors, but what it does make, it makes well. In our testing, this company’s formulas have consistently offered some of the best dosages and the best flavors we’ve encountered. Its Clean Stim-Free Pre-Workout is no exception.
The formula combines several well-studied performance ingredients into one transparent blend, pairing citrulline malate and arginine AKG to support nitric oxide production through complementary pathways. It rounds out the formula with betaine, beta-alanine, and several popular nootropic ingredients, including Alpha GPC and N-acetyl L-tyrosine.18
Some of the formula's highlights include:
- L-citrulline malate (2:1): 5,000mg
- Arginine AKG (2:1): 2,000mg
- Betaine anhydrous: 1,500mg
- Beta-alanine: 1,000mg
- N-acetyl L-tyrosine: 500mg
- Alpha GPC: 150mg
- Himalayan rock salt: 200mg
- BioPerine black pepper extract: 5mg
- Huperzine A: 200mcg
One ingredient worth mentioning is huperzine A. While the 200mcg dose used here appears to be well-tolerated by healthy adults, some experts recommend taking periodic breaks because huperzine A remains active in the body for many hours, and excessive acetylcholine activity may increase the risk of side effects such as headaches, nausea, and confusion.51 52
The company also offers a capsule-based NO booster that lacks some of the nootropic pre-workout ingredients found here and provides lower doses overall. In our opinion, the choice is clear: the Clean Stim-Free Pre-Workout powder is far superior.
Taste and mixability
Type Zero Clean Stim-Free Pre-Workout is our out-and-out winner for taste. This has been true for pretty much every category in which one of its supplements has made an appearance. The flavors available for its NO booster are:
- Fruit punch
- Pineapple mango
Type Zero's powder mixes very well into water. While it isn't quite as seamless as a single-ingredient amino acid like Kaged L-Citrulline or Nutricost L-Arginine, it still dissolves quickly with minimal clumping and was among the best-mixing multi-ingredient formulas we tested.
Pricing
Type Zero isn't the least expensive nitric oxide supplement in our guide, but it's one of the most comprehensive. A one-time purchase costs $29.99 for 21 servings ($1.43 per serving). Choosing a subscription saves 20%, bringing the cost down to $23.99, or about $1.14 per serving.
Additionally, readers can save an extra 15% with our exclusive INNERBODY15 promo code.
Type Zero also backs its products with a 60-day money-back guarantee, giving you plenty of time to decide whether it's the right fit. Shipping is free on orders of $50 or more, so purchasing two tubs or bundling products qualifies for free standard shipping. Otherwise, standard shipping starts at $5.
HumanN SPORT Pre-Workout
Best beetroot option
Image by Innerbody Research
Pros
- More than 9g of beetroot extract per serving
- Bulk and subscription discounts available
- Third-party tested for contaminants and dosage
- Rich cherry flavor is just sweet enough
- Gluten-free, vegan, and non-GMO
- Good source of vitamin C
- Sweetened with stevia
Cons
- Exact beetroot dose is unclear
- May not fit keto or fasting protocols
- Will stain anything it touches
- Slowest shipping of the products we tested
HumanN has built its brand around one ingredient: beets. While the company also sells a handful of greens, turmeric, and vitamin products, its core lineup is devoted to beet-based supplements in powders, gummies, chews, and tablets.
Beetroot is one of the best-studied natural sources of dietary nitrate.7 After you consume it, nitrate is converted into nitrite and then nitric oxide, a molecule that helps relax blood vessels, improve circulation, and support exercise performance. That's why beetroot has become a staple ingredient in many nitric oxide supplements and pre-workouts.
HumanN Sport (formerly SuperBeets Sport and, before that, BeetElite) is the company's performance-focused formula. It's NSF Certified for Sport, meaning it has been independently tested for substances banned by major athletic organizations, but its benefits aren't limited to competitive athletes. Anyone looking to increase their dietary nitrate intake can potentially benefit from its concentrated beetroot formula.
One thing HumanN doesn't disclose is exactly how much beetroot powder each serving contains. The total serving size is 10g, however, and when we contacted the company through its live chat, a representative confirmed that a little less than 1g comes from the other ingredients, including natural cherry flavor and magnesium ascorbate. That leaves more than 9g of beetroot powder per serving, making it one of the highest-dose beet formulas we've evaluated.
HumanN's product also stands apart because it's supported by company-sponsored clinical research. While manufacturer-funded studies should always be interpreted with appropriate caution, they can still provide valuable insight when they're well designed. HumanN has published research showing:
- Original SuperBeets (at roughly half the beetroot dose found in HumanN Sport) lowered blood pressure after four weeks of daily use in healthy adults.26
- BeetElite, the original name for HumanN Sport, increased total work performed and delayed exhaustion during high-intensity interval exercise compared to placebo, suggesting improved exercise capacity.39
Although these studies were funded by HumanN, the trial designs appear methodologically sound and help support the product's intended uses alongside the broader body of research on dietary nitrate and beetroot supplementation.
Taste and mixability
HumanN Sport was one of our testers' favorite-tasting products in this guide, finishing second only to Type Zero. Rather than trying to mask the natural beet flavor with excessive sweetness, HumanN leans into it. The Wild Cherry flavor and stevia provide just enough sweetness to complement the earthy beet profile without overpowering it.
That's good news if you enjoy the taste of beets, but it's something to keep in mind if you don't. Unlike some flavored pre-workouts, HumanN Sport still tastes unmistakably like beetroot — the cherry flavor simply rounds out the edges.
Mixability was also excellent. It takes a little stirring, but the powder dissolves completely in the recommended amount of water. It left virtually no grit or sediment by the time we finished our drinks.
Pricing
HumanN has made Sport much more competitive since our last review by adding both bulk purchase and subscription discounts. A single canister costs $39.95 (about $2 per serving), while purchasing multiple canisters or subscribing can significantly reduce the cost per serving. Subscription orders also include free shipping and can be adjusted or canceled at any time.
That breaks down like this:
| Total price | Price per serving | |
|---|---|---|
| One-time (1 canister) | $39.95 | $2.00 |
| One-time (3 canisters, 9% off) | $109.06 | $1.82 |
| One-time (6 canisters, 15% off) | $203.75 | $1.70 |
| Subscription (1 canister, 10% off) | $35.96 | $1.80 |
| Subscription (3 canisters, 18% off) | $98.16 | $1.64 |
| Subscription (6 canisters, 24% off) | $183.40 | $1.53 |
One-time purchases incur an $8.95 shipping fee, though orders over $75 ship free. All subscription orders include free shipping, making them the best overall value.
HumanN also continues to offer the longest money-back guarantee in this guide. Its 90-day satisfaction guarantee gives you ample time to determine whether HumanN Sport is a good fit, which is especially reassuring if you're new to beet supplements or aren't sure you'll enjoy their distinctive flavor.
Kaged L-Citrulline
Best budget pick
Image by Innerbody Research
Pros
- Pure L-citrulline formula backed by strong research for nitric oxide production
- Informed Sport Certified and third-party tested
- 100 servings per container
- Save 20% on your first subscription order, then 10% on future deliveries
- Free shipping with subscriptions
Cons
- Available only as an unflavored powder
- The 2g serving is lower than the doses used in many exercise performance studies
- Standard shipping costs about $8 without a subscription
Founded in 2015, Kaged has built a reputation for producing sports supplements that combine strong quality control with research-backed ingredients. Its L-Citrulline powder is a great example. Rather than combining several ingredients into a proprietary blend, Kaged focuses on a single nitric oxide precursor with one of the strongest bodies of evidence behind it. There are two key reasons L-citrulline has become the preferred standalone nitric oxide ingredient:
- While both L-citrulline and L-arginine can increase nitric oxide production, oral L-citrulline is generally considered the more effective supplement. That's because much of the L-arginine you consume is broken down in the intestine and liver before it ever reaches circulation, limiting how much is ultimately available to produce nitric oxide.37
- L-citrulline largely bypasses this first-pass metabolism. After absorption, it's converted into L-arginine by the kidneys, producing a larger and more sustained increase in circulating arginine — the amino acid your body uses to generate nitric oxide.38
Kaged uses fermented L-citrulline, a vegan-friendly ingredient produced through microbial fermentation rather than chemical synthesis. While fermentation hasn't been shown to improve absorption or effectiveness, it's commonly used to produce high-purity amino acids.
Each serving provides 2g of L-citrulline. That's below the 6-8g commonly used in studies examining exercise performance, but it also gives users flexibility.38 Because each container provides 100 servings at one of the lowest prices in our guide, it's easy to increase the serving size based on your goals while still paying considerably less than you would for most multi-ingredient nitric oxide formulas.
Taste and mixability
Kaged L-Citrulline mixes exceptionally well. After just a few seconds of stirring, very little residue remained, producing one of the smoothest drinks in our testing. There was virtually no grit left behind, and the powder stayed well dissolved from the first sip to the last.
The powder is also practically tasteless. On its own, there's only the faintest hint of tartness, but it's subtle enough that most people are unlikely to notice it. When mixed into juice, a smoothie, or another flavored beverage, it becomes virtually undetectable.
Pricing
Where Kaged really stands out is price.
| Price | Cost per serving | |
|---|---|---|
| One-time purchase | $15.00 | $0.15 |
| First subscription order (20% off) | $12.00 | $0.12 |
| Recurring subscription (10% off) | $13.50 | $0.14 |
At just $15 for 100 servings, Kaged offers one of the lowest per-serving prices in this guide. Choosing a subscription drops the cost to $12 ($0.12 per serving), includes free shipping, and lets you select deliveries every 4, 6, or 8 weeks. After the initial order, subscriptions continue at 10% off ($0.14 per serving) and can be paused, modified, or canceled at any time. Customers who prefer a one-time purchase should expect to pay about $8 for standard shipping.
Kaged also backs its supplements with a 60-day money-back guarantee, matching Type Zero and offering more protection than Gorilla Mind, which doesn't provide a satisfaction guarantee.
Gorilla Mind’s Gorilla Mode Nitric
Best pre-workout
Image by Innerbody Research
Pros
- Targets nitric oxide through multiple complementary pathways
- Includes complementary workout ingredients like creatine and betaine
- Third-party tested, with results posted online
- Added electrolytes to support hydration
- Available in 13 flavors
- Subscription discounts with free shipping
Cons
- Taste can come across as overly sweet or artificial
- No money-back guarantee
Gorilla Mode Nitric is Gorilla Mind's flagship stimulant-free pre-workout. While the company offers several products designed to enhance exercise performance, this formula takes a comprehensive approach to nitric oxide production by combining ingredients that work through multiple complementary pathways. Rather than relying on a single nitric oxide precursor, Gorilla Mode Nitric pairs L-citrulline with dietary nitrate while also including several well-studied ingredients that may support strength, endurance, hydration, and muscle pumps.
Some of the formula's highlights include:
- L-Citrulline (5,000mg): One of the best-studied nitric oxide precursors, L-citrulline reliably raises blood arginine levels, allowing your body to produce more nitric oxide than oral L-arginine supplementation alone.34
- Creatine monohydrate (2,500mg): One of the most extensively studied sports supplements available, creatine consistently improves strength, power output, and high-intensity exercise performance when taken regularly.19
- Betaine anhydrous (2,000mg): Betaine has been associated with improvements in muscular endurance, power output, and training volume in several clinical studies.24
- HydroPrime Glycerol Powder (2,000mg): A branded glycerol ingredient intended to increase hydration and support the muscle "pump" many athletes seek during training.40
- Taurine (1,500mg): Taurine is a common addition to pre-workout formulas because research suggests it may support endurance, reduce fatigue, and improve exercise performance.41
- Agmatine sulfate (500mg): Agmatine sulfate is a naturally occurring metabolite of L-arginine that's commonly included in nitric oxide supplements for its potential to support blood flow and exercise performance.49
- Sodium nitrate (750mg): Dietary nitrate follows a separate nitrate-nitrite-nitric oxide pathway, complementing L-citrulline by increasing nitric oxide availability through an independent mechanism.42
- VasoDrive-AP (254mg): These milk-derived bioactive peptides have been studied for their ability to promote healthy vascular function and support normal blood pressure in healthy adults.43
Several of these ingredients are included at or near doses commonly used in human research, particularly betaine, glycerol, and VasoDrive-AP. While the 5g of L-citrulline falls just below the 6-8g often used in exercise studies, it's still a substantial dose, especially when paired with dietary nitrate. Likewise, the 2.5g of creatine doesn't quite reach the typical 3-5g daily maintenance dose, but it can still contribute meaningfully if you're already supplementing with creatine or consistently using Gorilla Mode Nitric as your pre-workout.
Taste and mixability
In much the same way that HumanN SPORT Pre-Workout's earthy beet flavor may not appeal to everyone, Gorilla Mode Nitric's sweetness proved divisive among our testers. There's no shortage of options to choose from (13 flavors in total), but all of the ones we've tried are artificially flavored and sweetened with sucralose. The result is a very sweet, almost candy-like beverage that some testers enjoyed, while others found overly sweet.
Gorilla Mode Nitric mixes exceptionally well with water, leaving virtually no grit or sediment behind. That's a good thing, because its intensely sweet flavors don't lend themselves particularly well to mixing into other beverages.
Pricing
Gorilla Mind offers savings through both subscriptions and bulk purchases, though they're not quite as generous as those of some competitors. For example, Type Zero discounts subscriptions by 20%, compared to Gorilla Mind's 10%.
| Total price | Cost per serving | |
|---|---|---|
| One-time purchase | $59.99 | $1.50 |
| Subscription (10% off) | $53.99 | $1.35 |
Shipping costs $9.95 on one-time purchases under $75. Orders over that threshold ship free, and all subscription orders include free shipping regardless of order size.
Gorilla Mind's return policy is considerably less generous than those of several other companies in this guide. The company accepts returns only for unopened products within 30 days and doesn't offer a money-back guarantee if you've already tried the product. By comparison, Type Zero offers a 60-day money-back guarantee, while HumanN extends its guarantee to 90 days.
Nutricost L-Arginine Powder
Best for erectile dysfunction
Photo by Innerbody Research
Pros
- Provides 5g of pure L-arginine per serving
- Dose closely matches those used in many ED clinical trials
- Unflavored powder mixes well into beverages
- Just $0.30 per serving
- Third-party tested
- Vegan and gluten-free
Cons
- Benefits appear greatest in men with mild to moderate ED
- No additional nitric oxide ingredients
- Slightly bitter taste on its own
Nitric oxide plays a central role in erectile function by relaxing the smooth muscle within the penis and allowing blood vessels to dilate. In fact, medications like sildenafil (Viagra) work in part by enhancing the effects of nitric oxide rather than creating erections independently. That connection has led researchers to investigate whether increasing nitric oxide through supplementation can improve erectile function, particularly in men with mild to moderate erectile dysfunction.
Among over-the-counter ingredients, L-arginine has the strongest body of evidence for this specific use. While L-citrulline often does a better job of raising circulating arginine levels, the majority of clinical trials evaluating erectile dysfunction have used L-arginine, typically at doses between 3g and 6g per day, with 5g being one of the most commonly studied amounts.36
That's exactly what Nutricost delivers in a single scoop. Rather than combining smaller amounts of several nitric oxide ingredients, it provides a straightforward 5g serving of pure L-arginine, making it easy to match the doses used in much of the published research. For readers specifically interested in erectile function, we think that's a more evidence-based approach than relying on blends or lower-dose combinations.
Of course, L-arginine isn't a replacement for prescription ED medications, and it won't work for everyone. However, systematic reviews suggest it may meaningfully improve erectile function, particularly among men with mild to moderate ED, with greater benefits observed when higher doses are used consistently.
Taste and mixability
Like Kaged's L-citrulline, Nutricost L-Arginine mixes exceptionally well. After just a few seconds of stirring, very little residue remained, producing a smooth drink with virtually no grit left behind. The powder stayed well suspended from the first sip to the last, making it easy to mix into water or your beverage of choice.
The biggest drawback compared with Kaged's L-citrulline is the taste. Whereas Kaged is practically flavorless, Nutricost's L-arginine has a distinctly bitter taste that our testing team didn't enjoy drinking in plain water. Mixing it into juice, a smoothie, or another flavored beverage can help mask some of the bitterness. If taste is a deciding factor, we'd lean toward Kaged's L-citrulline. Although L-arginine has been studied much more extensively for erectile dysfunction, early research suggests L-citrulline may also provide benefits in some men.50
Pricing
At $14.97 for 50 servings, Nutricost L-Arginine is one of the least expensive products in our guide, costing just $0.30 per serving despite providing a clinically relevant 5g dose. Readers who expect to use it long term can save even more by purchasing one of the larger container sizes or signing up for a subscription.
| Total price | Cost per serving | |
|---|---|---|
| 250g (One-time) | $14.97 | $0.30 |
| 500g (One-time) | $24.97 | $0.25 |
| 1kg (One-time) | $38.97 | $0.19 |
| 250g (Subscription) | $11.98 | $0.24 |
| 500g (Subscription) | $19.98 | $0.20 |
| 1kg (Subscription) | $31.18 | $0.16 |
Orders over $59 qualify for free shipping; otherwise, standard shipping costs $7. Nutricost also lets you schedule subscriptions every 30 days, two months, or four months, and those options make more sense than they might initially appear.
At the recommended 5g serving, the 250g tub lasts about 50 days, making the two-month subscription the most practical option for most users. The larger tubs make the most sense if you're taking higher daily doses (around 8-10g), which are similar to those used in some exercise-performance studies.
Alternatives to nitric oxide supplements
Nitric oxide supplements can be an effective way to support blood flow, exercise performance, and cardiovascular health, but they aren't always the best solution for every goal. Depending on what you're trying to accomplish, one of the alternatives below may be a better fit — or may complement a nitric oxide supplement as part of a broader wellness strategy.
Creatine
If your primary goal is to build muscle, increase strength, or improve high-intensity exercise performance, creatine monohydrate has substantially stronger evidence than nitric oxide supplements. Hundreds of clinical trials have demonstrated improvements in strength, power output, lean muscle mass, and repeated sprint performance, making creatine one of the most extensively researched sports supplements available.19
That doesn't mean nitric oxide supplements are ineffective — they may improve endurance, blood flow, and the "muscle pump" many people enjoy during training — but if you could choose only one performance supplement, creatine would be the more evidence-based option for most people. We cover the science in greater detail in our guide to the best creatine supplements.
Erectile dysfunction medications
Nitric oxide plays a central role in achieving and maintaining an erection, but prescription medications such as sildenafil (Viagra) and tadalafil (Cialis) have considerably stronger evidence for treating erectile dysfunction. Rather than increasing nitric oxide production, these medications prolong nitric oxide's effects by preventing the breakdown of cyclic GMP (cGMP), allowing blood vessels in the penis to remain relaxed for longer.45
Because both nitric oxide supplements and PDE5 inhibitors can lower blood pressure, they shouldn't be combined without first speaking with your healthcare provider. If you're considering prescription treatment, our guide to the best erectile dysfunction treatments explains how these medications compare.
CoQ10
If your primary concern is cardiovascular health rather than athletic performance, coenzyme Q10 (CoQ10) may be worth considering. Unlike nitric oxide supplements, CoQ10 doesn't directly increase nitric oxide production. Instead, it supports mitochondrial energy production while helping reduce oxidative stress, which may improve endothelial function and preserve nitric oxide availability.46 Clinical studies have also associated CoQ10 supplementation with modest improvements in blood pressure and other markers of cardiovascular health.47
If you'd like to learn more, we've also reviewed the best CoQ10 supplements and the research supporting them.
Diet and lifestyle
No supplement can replace the benefits of healthy lifestyle habits. Regular aerobic exercise naturally stimulates nitric oxide production by increasing blood flow and activating endothelial nitric oxide synthase (eNOS), while a diet rich in vegetables provides the dietary nitrates your body needs to produce nitric oxide.23 48
Some of the best dietary sources of nitrate include:
- Beets
- Arugula
- Spinach
- Bok choy
- Swiss chard
- Lettuce
- Celery
Other foods that may support healthy nitric oxide production include citrus fruits, pomegranate, garlic, and watermelon, which naturally contain L-citrulline.
Nitric oxide supplement FAQ
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Innerbody uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
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