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Thesis Nootropics Review

Thesis has a range of targeted nootropics you can combine to optimize your results. How do you know which ones to pick? Our testing team will help you decide.

Last Updated: May 4, 2022
Thesis Nootropics

Many people would admit that their minds don’t perform quite as well as they get older. Maybe you forget simple things like where you put your keys. Or perhaps you have trouble finding just the right word for something with increased frequency. It can be a frustrating and demoralizing experience.

Nootropics offer their users the potential to improve their cognitive abilities and regulate their moods. They don’t require prescriptions, and they consist of ingredients that research says are mostly safe and effective.

Thesis boasts a lineup of nootropics that they’ve blended to target specific cognitive, emotional, or wellness goals. They make it easy to get started with a helpful quiz and a starter pack that lets you try four of their six combinations. In this review, we’ll compare their blends and help you figure out whether their products are right for you.

Review Summary


  • Products are third-party-tested
  • Six formulas to choose from
  • All formulas available without stimulants
  • Outstanding phone support
  • Subscriptions include complimentary wellness coaching
  • Free shipping
  • Use code INNERBODY for 10% off your first order


  • Money-back guarantee is only 30 days
  • You have to start with the starter pack
  • A little more expensive than competitors

Bottom line

Thesis’ ingredient combinations are thorough enough to provide tangible benefits without introducing too many new compounds to your system. Their subscription structure lets you customize your deliveries and ensures you have a full stock of whatever formulas you find most useful. As long as you don’t mind paying a few extra dollars per month compared to some competitors, we recommend Thesis as an ideal place to start if you’re curious about what nootropics can do for you.

Our Top Picks


Thesis offers six nootropics formulas to target everything from cognition and memory to focus and creativity.

Each nootropic formula has a distinct ingredient profile, and has been third party tested. Take 10% off your first order with code INNERBODY at checkout.

Thesis Clarity
Reviewed by Innerbody Research
Thesis Logic
Reviewed by Innerbody Research
Thesis Energy
Reviewed by Innerbody Research

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Over the past two decades, Innerbody Research has helped tens of millions of readers make more informed decisions about staying healthy and living healthier lifestyles.

We extensively test each health service or product we review. Our content provides you, our readers, with an unbiased exploration of at-home health options, free of marketing jargon or gimmicks. We evaluate products and services based on their adherence to quality and the latest medical evidence and health standards. We ask ourselves two simple questions: Would we buy the product or service ourselves if it weren’t part of our job? Would we recommend it to family and friends?

Additionally, like all health-related content on this website, this review was thoroughly vetted by one or more members of our Medical Review Board for accuracy.

What are nootropics?

Nootropic is a term most people use to refer to any non-prescription supplement that can boost brainpower. The technical definition is a little more nuanced — encompassing prescription medications like Ritalin and Adderall — but the supplement industry has largely co-opted it to categorize non-prescription products.

Most nootropic supplements contain botanical ingredients, vitamins, minerals, and amino acids that boast at least some clinical research connecting them with improvements in any of the following:

  • Cognition
  • Memory
  • Learning
  • Anxiety
  • Depression
  • Focus
  • Creativity

Compared to their prescription cousins, nootropic supplements aren’t particularly strong. Still, clinical research and our internal testing indicate a tangible benefit to taking them.

What is Thesis?

Thesis is a supplement company with a focus on nootropics. Their founders each had experiences growing up with what would today be considered learning disabilities, and they credit nootropics for changing their lives. They make six distinct nootropic formulas, each with a specific ingredient profile.

Thesis differentiates themselves from their competitors in several critical ways.

  1. They offer a starter kit containing a personalized combination of blends.

  2. They have the option to remove caffeine by request from any formula.

  3. They provide some of the best phone support we’ve ever experienced.

  4. Their targeted formulas conform to changing needs.

By providing you with a mix of formulas for your various needs, Thesis gives you the ability to enhance the aspects of your cognitive and emotional life that need it the most on any given day.

Maybe you know you have low energy levels on Mondays and Wednesdays, so you can take the Energy formula on those days. Maybe you want to devote your weekends to artistic pursuits. You can use the Creativity blend for that. Or you might find that one of their six blends works well for you in any situation. In that case, you can adjust your order so you receive only that formula.

Our testers appreciate that Thesis phone support is responsive, friendly, and intelligent. They rarely waited more than a minute to speak to someone, and the sense we got talking to them was that the company keeps their team streamlined with exceedingly bright employees.

Thesis uses an impressive set of ingredients backed by respectable clinical research.

Here’s a look at some of the ingredients you’ll find in Thesis nootropics:


Several studies show that dihydrohonokiol-B (DHH-B) has potent anxiolytic effects. That means it can combat anxiety, with results in as little as one hour after treatment.

Saffron (Affron)

Saffron offers multiple benefits to users, including increased levels of dopamine and glutamate that are dose-dependent. Human studies have also shown positive effects in Alzheimer’s patients.


Derived from a South African plant, Zembrin provides cognitive and anti-anxiety effects in clinical trials that used the same 25mg dose found in Thesis Creativity.


Synapsa is a patented form of Bacopa extract, a traditional Ayurvedic memory enhancer. Studies resulted in statistically significant improvements in cognitive tests administered throughout the trial.

7,8 DHF

7, 8 DHF is a small molecular TrkB agonist that can easily cross the blood-brain barrier. It can increase brain-derived neurotrophic factor (BDNF), a deficiency of which is connected to numerous cognitive ailments.


Choline is a precursor to acetylcholine, a powerful neurotransmitter in the peripheral, autonomic, and enteric nervous systems. Various studies conclude that choline supplementation can strengthen cognitive performance.


While studies suggest that people with higher levels of DHA are less likely to develop Alzheimer’s, clinical trials indicate that its effects are almost exclusively prophylactic. That means it won’t necessarily improve cognitive function, but it can protect it.

Alpha GPC

Like choline, Alpha GPC acts as an effective acetylcholine precursor. Studies also show that supplementation with Alpha GPC can stave off exercise-induced reductions in choline levels.


In addition to being an effective treatment for neuropathic pain, agmatine appears to have potent effects as a natural antidepressant. A five-year safety study concluded that there are no long-term side effect risks.


Research into epicatechin indicates that it can enhance cerebral blood flow, delivering more oxygen to the brain to ensure it operates at its highest efficiency.

Lion’s mane

Lion’s mane has been shown to increase nerve growth factor and promote neurite outgrowth of specific neural cells. It’s a safe and reliable neurotrophic, but studies have debunked claims of neuroprotective properties.


Hyperphenylalaninemia, a severe deficiency in phenylalanine, results in reduced dopamine, serotonin, and noradrenaline levels in the brain. It can also alter cerebral myelin and protein synthesis. Supplementing with phenylalanine should provide neuroprotective benefits.

Thesis nootropic formulas

Thesis has six nootropic formulas in their lineup. Each one has a blend of ingredients that addresses specific needs. Their names give you a pretty big clue as to what the company intends each to do, but a closer look at their ingredients will help you understand how they achieve this.

Their formulas are:

  • Clarity
  • Logic
  • Energy
  • Motivation
  • Creativity
  • Confidence

Interestingly, the company thinks of its formulas as working well in pairs.


Enhances focus, eliminates brain fog, and lets thoughts flow naturally.


Gets you going, keeps you going, and never crashes.


Sparks new ideas, inspires extroversion, and revels in openness.

Of course, you’re free to mix and match formulas as you see fit. And you’ll usually only take one formula at a time. But these pairs act synergistically for specific personality types or cognitive needs.

Let’s take a closer look at each formula.

Thesis Clarity

Thesis Clarity relies on 7,8 DHF, Alpha GPC, epicatechin, and lion’s mane to increase blood flow to the brain and stimulate the production of acetylcholine, a powerful neurotransmitter. It’s particularly adept at cutting through brain fog.

Here’s a look at Clarity’s full ingredients list:

  • 7,8-DHF (30mg)
  • Alpha GPC (250mg)
  • Epicatechin (250mg)
  • Lion’s Mane (500mg)
  • Caffeine (100mg)
  • L-theanine (200mg)

Thesis Logic

Thesis Logic contains triacetyluridine (TAU), which caters to the health of the entire central nervous system. It also uses phosphatidylserine to help facilitate communication between and protection of brain cells.

This is Logic’s complete ingredients list:

  • TAU (30mg)
  • DHA (200mg)
  • Phosphatidylserine (200mg)
  • Theobromine (100mg)
  • Ginkgo biloba (160mg)
  • Synapsa (320mg)
  • Caffeine (100mg)
  • L-theanine (200mg)

Thesis Energy

Thesis Energy uses cysteine and tyrosine alongside its caffeine to deliver a steady energy supply. It also includes TeaCrine, a branded form of theacrine, which partners with caffeine to affect adenosine signaling and prevent fatigue.

Here’s a full list of Energy’s ingredients:

  • Choline (300mg)
  • NAC (500mg)
  • NALT (300mg)
  • Sabroxy (100mg)
  • TeaCrine (100mg)
  • Zynamite (300mg)
  • Caffeine (100mg)
  • L-theanine (200mg)

Thesis Motivation

Blood flow and cellular function are at the core of Thesis Motivation. It employs artichoke extract, forskolin, and B12 to achieve these goals, with a healthy dose of phenylalanine for added focus and motivation.

Here’s Motivation’s full ingredients list:

  • Artichoke Extract (450mg)
  • Dynamine (100mg)
  • Forskolin (250mg)
  • L-Phenylalanine (500mg)
  • B12 (1,000mcg)
  • Caffeine (100mg)
  • L-theanine (200mg)

Thesis Creativity

Thesis Creativity realigns you with your inspiration by removing barriers caused by stress, anxiety, and depression. It contains ingredients with powerful anxiolytic properties and 5-HT reuptake inhibition.

Here’s a look at the whole Creativity ingredients list:

  • Agmatine (250mg)
  • Alpha GPC (150mg)
  • Ginseng (200mg)
  • Ashwagandha (300mg)
  • Zembrin® (25mg)
  • Caffeine (100mg)
  • L-theanine (200mg)

Thesis Confidence

Thesis has yet to advertise a new formula called Confidence as of this writing. It’s designed to work hand-in-hand with Creativity, using saffron and DHH-B to increase dopamine levels and decrease anxiety.

Here is Confidence’s complete ingredients list:

  • Zembrin (25mg)
  • DHH-B (10mg)
  • Affron (28mg)
  • Ashwagandha (120mg)
  • Magnesium L-Threonate (500mg)
  • Sage Extract (333mg)
  • Caffeine (100mg)
  • L-Theanine (200mg)

Caffeine and L-theanine

While every formula is different, you’ll notice that each one contains both caffeine and L-theanine. The nootropic properties of caffeine are well-established. L-theanine — a non-stimulant derived from green tea — has been shown to smooth out the jittery effects of caffeine. You can easily have caffeine removed from any Thesis formula for no extra cost. The L-theanine will remain, as it has its own set of cognitive benefits in addition to its ability to tame caffeine.

Thesis Nootropics pricing, shipping, and returns

Thesis keeps their price structure decidedly simple. This is refreshing considering the range of nootropics they offer. You don’t have to worry about one style costing you more than another.

Here’s how it works:

  • Any one-time purchase of a one-month supply, including the starter kit, costs $119.
  • When you subscribe, that monthly cost drops from $119 to $79.

Shipping from Thesis is free in the US, and the company offers a 30-day money-back guarantee.

Getting started with Thesis Nootropics

Setting up a subscription with Thesis is a straightforward process. Here are the basic steps:

  1. Take the Thesis quiz. This will create a starter kit specific to your results.

  2. Order your starter kit. We recommend going with the kit Thesis creates after your quiz, but you can call or email them after placing your order to make any changes to the formula combination before it ships.

  3. Set up a coaching consultation. We recommend having your first consultation before your kit arrives to be completely prepared.

  4. Take your nootropics as needed. Most people can experience some of Thesis nootropics’ benefits within a few hours of ingestion. Some ingredients and formulas may take a few days to produce results.

  5. Refine your order. As you near the end of your first month, you can head over to the Thesis website and customize your next order to include the formula or formulas you like most.

  6. Set up follow-up consultations as needed. These will help you refine your future orders and maximize your results.

When you subscribe to the starter kit, you will continue receiving the that kit every month until you customize your order. Thesis divides their boxes into four one-week supplies, and you can mix and match those supplies to suit your needs.

For example, you could boost energy on the weekdays and creativity on the weekends by getting a one-month supply with 21 servings of Energy in three one-week packages, and seven servings of Creativity in a single one-week package.

Personalized insights and coaching

When you take the quiz on the Thesis website, you’ll get personalized insights comparing your results to other quiz-takers and a data set developed from 472 scientific studies. The parameters in your results cover:

  • Energy
  • Focus
  • Motivation
  • Memory
  • Mood
  • Sleep

These results inform the system to make recommendations for your starter kit. After you order, you can set up a consultation with a Thesis coach. These consultations are free, and you can have as many follow-up sessions as you like.

Consultation calls last around 15 minutes, though some of our testers had their sessions go longer as their coaches’ schedules allowed. We received best practices information about taking nootropics that covered dose timing, formula application, and more. Some of our testers also received diet and exercise advice that coincided with their formulas.

Alternatives to Thesis

Thesis is far from the only game in town. And they are among the more expensive nootropics out there. Still, we think their system — the targeted formulas, free consultations, and so on — adds tremendous value.

If you’re curious about alternatives, here are a few to get you started.


TruBrain offers one of the widest varieties of nootropics of any company. They also have some novel and beneficial delivery methods for their nootropic ingredients. Those include energy bars and liquid shots that are outstanding for anyone who has difficulty swallowing pills.

TruBrain offers their nootropics in a targeted fashion, not unlike what you get from Thesis. They have a capsule supplement specifically designed to fight brain aging. And their shots are available in blends they call:

  • Sleep
  • Mellow
  • Mushrooms
  • Medium
  • Strong
  • Extra Strong

A 30-pack supply of TruBrain nootropic shots costs $69. That’s $10 less than the subscription cost for a one-month supply of Thesis. However, some of their shots contain caffeine, and others don’t. If it already contains caffeine, there’s no way to alter a TruBrain formula to be stimulant-free.

Qualia Mind

Qualia Mind is a brand under the Neurohacker Collective, a company that offers several products to address things like sleep quality, skin health, and vision. They have three nootropics available:

  • Qualia Mind
  • Qualia Mind Caffeine-Free
  • Qualia Mind Essentials

Initial shipments from Qualia mind are significantly discounted, but after the first month, the price makes theirs one of the most expensive nootropics we’ve tested. For example, the first month of a subscription to Qualia Mind costs just $39. After that, it costs $119/month. And a one-time purchase is $139.

To be fair, their blend is comprehensive, consisting of nearly 30 ingredients in high doses. That means it’s liable to provide you with noticeable effects. It also means you might not know which of those effects are coming from which ingredients, and some of the less beneficial components in your body may also have side effects you’d rather avoid.

Hunter Focus

Hunter Focus is one of three supplements in the Hunter stack alongside the company’s Test and Burn supplements. The stack is intended for male use — Test is a testosterone supplement — but Focus is suitable for men and women alike.

Like Qualia Mind, Focus has a long list of ingredients in generous doses. In fact, one serving of Hunter Focus is kind of like taking all six of Thesis’ formulas at once. That said, the serving itself is a bit difficult to swallow, as it consists of six large pills.

Another knock on Hunter is that they don’t offer any subscription system. That means you can’t get any extra discount, and you have to remember to reorder when you’re running low (though theoretically, a nootropic like this should boost your memory).

One bottle of Hunter Focus costs $80, and shipping is $7.95 unless you buy more than one bottle at a time. If you buy three bottles at once, the company will throw a fourth in for free. That’s really the only way to get any savings through Hunter.

How we evaluate health products and services

At Innerbody Research, we customize our evaluation criteria depending on the type and nature of the health-related service or product. In general, we have five broad evaluation areas, including:

Quality: How well does the company deliver its core service(s) or product(s)? How is advanced technology used for accuracy and safety? What evidence of effectiveness exists to justify the company’s approach? Are manufacturing standards of high quality?

User-friendliness: How intuitive and convenient is the service or product? To what degree is the company interface helpful and understandable?

Value: Are you getting your money’s worth? Are there any hidden costs or charges? Does the company offer discounts?

Privacy: If health data is stored, is it stored securely? Are payments secure? Does the company market your information?

Customer support: With personalized products and services, how well does the company address your individual needs? If a product or service does not work for you, are there satisfaction guarantees or return policies that protect you?

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