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Rugiet Reviews: Are these lozenges the ED solution for you?

Rugiet combines two of the most popular ED medications with a third drug, packaged in a convenient lozenge. Find out if Rugiet is right for you.

Last Updated: Apr 13, 2022
Rugiet Reviews

Erectile dysfunction (ED) afflicts enough men in the world that none should feel any shame around it. But in those intimate moments between you and your partner, a failure to perform can feel incredibly isolating. Fortunately, several ED medications have proven safe and effective in providing men the ability to attain and sustain a healthy erection.

Sildenafil and tadalafil are two of the most common ED medications. Many would recognize their brand names: Viagra and Cialis. While most companies provide these medications in pill form, a few providers have alternative delivery methods that are far more convenient.

One of those companies is Rugiet, and their delivery method isn’t a pill but a lozenge. Their lozenges contain both sildenafil and tadalafil, as well as a third ED medication called apomorphine. Could this combination be the key to unlocking your lost potential in bed, and does it outperform competitors? Our research team compares this unique offering to the rest of the market’s options so you can find out.

Review Summary


  • Extremely easy to take
  • Effective for up to 36 hours
  • Free doctor consultation
  • Multiple mechanisms of action
  • Various dose options
  • Portable packaging
  • Pleasant minty flavor


  • Lozenges melt in higher temperatures
  • Combination of meds brings higher chance of side effects than individual meds
  • Expensive for the quantity you get

Bottom line

Rugiet Ready lozenges are a novel and impressive delivery method for a combination of well-researched drugs that is likely a safe and effective option for most users. Other players on the scene only provide one drug at a time, so this combination could help men who struggle to see results from any one medication on its own. Rugiet is an effective ED treatment.

Rugiet is a company to watch, but most men would probably find satisfaction with just one of the three drugs in Rugiet. For single drug treatments, BlueChew’s chewables remain our recommendation. Rugiet boasts an impressive absorption rate, and the lozenges even taste good, but BlueChew’s chewables are stable at room temperature and can travel more easily, earning them practicality points. Even better, Innerbody readers get exclusive discounts on BlueChew orders, making them the more economical choice.

Our Recommendation

BlueChew Chewables

BlueChew lets men with ED get effective prescription treatments affordably and discreetly -- no trips to the doctor’s office or pharmacy.

These are unique chewable forms of sildenafil and tadalafil (same active ingredients in Viagra® and Cialis®), which are proven to work for most men with ED. You won't need to rush for a glass of water when the mood is right.

Current Deals: Use our exclusive INNERBODY code to get one free month of the Active Plan or $20 off any plan

Why you should trust us

Over the past two decades, Innerbody Research has helped tens of millions of readers make more informed decisions involving staying healthy and living healthier lifestyles.

We extensively test each health service or product we review. We try our best to give you, our readers, an unbiased exploration of at-home health options, free of marketing jargon or gimmicks. We evaluate products and services based on their adherence to quality, the latest medical evidence and health standards, and a simple question: would we buy the product or service ourselves if it weren’t part of our job, and would we recommend it to family and friends?

Additionally, like all health-related content on this website, this review was thoroughly vetted by one or more members of our Medical Review Board for accuracy.

What causes erectile dysfunction?

There are many potential causes of erectile dysfunction. In addition to genetic predisposition, men can suffer from ED due to any of the following:

  • Depression
  • Anxiety
  • Stress
  • Fatigue
  • Cardiovascular problems
  • Obesity

It’s essential to address any of these underlying issues along with any ED medication you might seek. Not only could treating these issues alleviate the majority of your ED symptoms, but that could, in turn, eliminate the need for ED meds in the first place. That would cut down on your risk of complications or adverse effects and remove any prescription medications’ practical and financial burden on you.

Wherever the cause of erectile dysfunction, the physical processes remain constant. The body fails to deliver adequate blood to the corpora cavernosa. That’s the spongy tissue that makes up the bulk of your penis. Without a rush of blood to this tissue, the penis will not expand and harden.

Most ED medications — prescription and non-prescription — seek to relax the blood vessels in this area of the body and increase blood flow in general. That creates an environment where physical and psychological arousal can result in a healthy erection.

How Rugiet works

Rugiet delivers its ED medications in lozenge form. This allows the drugs to absorb much more efficiently than in pill form. These few minutes can make a difference if you’re using them for immediate use — not long before intimacy. But it might not mean life or death if you’re aware enough to take your ED meds an hour or so before intercourse begins.

Unlike most prescription ED treatments that provide a single drug, Rugiet Ready utilizes a trio of key ingredients, boasting a large amount of clinical research demonstrating safety and efficacy. There are some caveats for potential users with specific medical conditions, but the treatment should be acceptable for most men.

The three ED medications included in every Rugiet lozenge are:

  • Sildenafil
  • Tadalafil
  • Apomorphine

Let’s look at each of these ingredients to paint a clear picture of how Rugiet Ready lozenges fight ED.


Sildenafil is the key ingredient in Viagra. It’s a prescription PDE-5 inhibitor, which reduces levels of the enzyme phosphodiesterase type 5. In the absence of this enzyme, the blood vessels running through the penis relax and allow for improved blood flow in response to arousal.

Typically, sildenafil starts working within 30 minutes, and its effect can last 4-6 hours.

Sildenafil has been studied extensively and prescribed widely, but can be dangerous if you have cardiovascular issues, especially high blood pressure. During your doctor’s consultation, you’ll want to divulge any cardiovascular diagnoses you’ve received and discuss whether DPE-5 inhibitors would be safe for you.

Other potential side effects of sildenafil include:

  • Headache
  • Nausea
  • Vomiting
  • Nosebleeds
  • Sore throat
  • Runny nose
  • Fever
  • Respiratory infection
  • Flushing
  • Trouble sleeping
  • Abnormally long-lasting erections


Like sildenafil, tadalafil is a PDE-5 inhibitor, but it works a little differently than sildenafil. It has a similar side effect profile, but its primary effects last longer. While sildenafil is active in your system for about 4-6 hours, tadalafil remains effective for 24-36 hours. That makes it a more convenient choice for a lot of users.

Tadalafil may have more pronounced contraindications than sildenafil, especially when combined with medicines that control blood pressure. Make sure your consulting doctor is aware of any medications you take for blood pressure or any heart conditions you may have before you take tadalafil.


Apomorphine is a less common ED medication than tadalafil or sildenafil. It’s not a PDE-5 inhibitor like those two are. Instead, apomorphine is a dopamine agonist, which means it helps stimulate dopamine activity in the brain. Specifically, the apomorphine in Rugiet stimulates the D4 dopamine receptor, which studies have concluded is directly involved with erectile function. It does this without stimulating other dopamine receptors.

Apomorphine is more commonly used as a treatment for advanced Parkinson’s disease. Those patients receive the drug via intramuscular injection in an average dose of 3 mg. They often experience significant nausea as a side effect, so much so that most of them also consume an antiemetic to fight it off.

Interestingly, the oral dose of apomorphine that shows the most promise with relatively low side effects is also 3 mg. Remember that oral administration of any kind — be it a pill or lozenge — is much slower and less efficient in absorption than an injection. Rugiet provides a 3 mg dose of apomorphine in all of its possible dosing configurations.

Potential side effects of apomorphine include:

  • Nausea
  • Vomiting
  • Constipation
  • Diarrhea
  • Headache
  • Runny nose
  • Weakness
  • Yawning

Rugiet dosage and cost

Rugiet offers their lozenges in four dose mixtures. Here’s a simple chart to show you how much of each:

  Cost Lozenge count Sildenafil Tadalafil Apomorphine
Low strength $80 6 40 mg 14 mg 3 mg
Medium strength $100 6 65 mg 22 mg 3 mg
Most popular $120 6 80 mg 22 mg 3 mg
Maximum strength $140 6 110 mg 22 mg 3 mg

You and your doctor can decide together how many lozenges you would need in a month, but the standard package comes with six. If you opt for 90-day automatic refills, Rugiet will take $70 off each shipment. Remember that $70 comes off a three-month supply, which can cost anywhere between $240 and $420 per shipment.

But if standalone sildenafil or tadalafil would have done the same job for you as the combination medicine, then Rugiet is undoubtedly more expensive than providers like BlueChew.

Here’s a look at how the cost breaks down per dose between BlueChew and Rugiet’s most affordable combination:

  Cost Dose count Cost per dose
Rugiet Ready S40/T14/APO3 $80 6 $13.33
BlueChew sildenafil 45 mg $30 6 $5.00
BlueChew tadalafil 9 mg $30 4 $7.50

Payment, shipping, and returns

Rugiet accepts payments via credit cards only, and they don’t take American Express. Shipping from Rugiet isn’t free, but it is fast. It’s also worth considering that they have to ship their product cold. Your package will contain reusable ice packs to keep the lozenges cool in transit. You don’t freeze them when they arrive. However, the company advises that you keep them in the refrigerator if the temperature in your home regularly exceeds 74 degrees, as temperatures higher than this can melt the lozenges.

Insider Tip: If your lozenges ship in particularly hot weather or you happen to let them melt in your home or even in your pocket, don’t despair. The medicine in them is still good; you’ll have to get them cold enough to harden in their packaging, but they’re still safe and effective.

Availability by state

Rugiet is not available in all 50 states in the US. Telemedicine rules prohibit their prescribing or shipping to certain locations. Here’s a current list of the 40 states and one district that are eligible to receive Rugiet Ready:

  • Alabama
  • Arizona
  • Arkansas
  • California
  • Colorado
  • Connecticut
  • Florida
  • Georgia
  • Hawaii
  • Illinois
  • Iowa
  • Kentucky
  • Louisiana
  • Maine
  • Maryland
  • Massachusetts
  • Michigan
  • Minnesota
  • Missouri
  • Nebraska
  • Nevada
  • New Jersey
  • New Mexico
  • New York
  • North Carolina
  • Ohio
  • Oklahoma
  • Oregon
  • Pennsylvania
  • Rhode Island
  • South Dakota
  • Tennessee
  • Texas
  • Vermont
  • Virginia
  • Washington
  • Washington, DC.
  • West Virginia
  • Wisconsin
  • Wyoming

HSA, FSA, and health insurance

The company is upfront about the fact that they don’t work directly with insurers and that customers would have to put in claims for out-of-network reimbursement. They also clearly state that you’re welcome to try an HSA or FSA card to make your purchase but that most such attempts are declined.

Is Rugiet safe?

It’s hard to say whether Rugiet’s combination of ED medications is as safe as each individual medication by itself. ED medications like sildenafil and tadalafil are quite safe for most men, as long as you don’t have an underlying cardiovascular condition. In practice, the lowest effective dose of any medicine is the safest — that’s how you minimize adverse effects. So, if sildenafil or tadalafil work well enough on their own, there’s no need to combine them. You’re not going to get extended performance out of either, and you certainly won’t get any kind of special erection from the combination.

In cases of severe ED in which a high dose of sildenafil or tadalafil barely works, it may be worth exploring the combination. There haven’t been a lot of studies on the combination of PDE-5 inhibitors. Still, a few studies showed greater reported satisfaction levels among participants with no noticeable uptick in side effects compared to PDE-5 inhibitors taken in isolation.

Those studies used lower doses of tadalafil and sildenafil than almost any of Rugiet’s available prescriptions. And that’s without the addition of apomorphine to the picture. Ultimately, we need to see many more studies on PDE-5 combinations at various doses before determining that Rugiet is safe for use.

Rugiet for daily use

Some doctors will prescribe tadalafil for daily consumption. These instances typically involve much lower doses than what is present in Rugiet Ready. Even before considering the presence of sildenafil and apomorphine, it would be dangerous to consume Rugiet Ready’s tadalafil dose daily. It would also be prohibitively expensive, as a daily dose of Rugiet Ready’s least powerful combination would cost you around $400/month.

Privacy considerations

Privacy is vital when it comes to sexual health. This is true online and in person. Rugiet will track your activity on their site using cookies, beacons, and other trackers, but they protect all significant personal data. That extends to health data, as well. While Rugiet is not considered a “covered entity” under HIPAA, their role as a “business associate” to pharmacies and medical groups ensures that your information is protected under the strictest standards.

Your shipment also provides added privacy. The medication comes in a box whose only identifying markers are your address and the return address of the issuing pharmacy. Nothing about the shipment would inform anyone, from parcel carriers to neighbors, about what’s inside.

Alternatives to Rugiet


Given the higher cost of this combination of drugs, as well as the potentially heightened probability of mild side effects, we recommend starting with sildenafil or tadalafil on their own if you’re seeking ED medication for the first time. BlueChew is currently our favorite provider of these two medications. They deliver their medications in a chewable form that is more convenient to take than a pill. These chewables are easy to travel with and can save you a good deal of money compared to other options, including Rugiet. Innerbody readers even get an exclusive discount on BlueChew.

For more information, check out our comprehensive BlueChew review.

Testosterone boosters

Low levels of testosterone can often cause performance issues in the bedroom. Before you start down the path of prescription medications, getting your testosterone levels checked may be worth it. You have a whole host of treatment options if they’re low, from prescription testosterone supplements to boosters made entirely of natural ingredients. Innerbody readers can get discounts on several boosters and at-home testosterone tests you can take in comfort and convenience.

To learn more about testosterone boosters, check out our guide to the best of them. And to find out which at-home testosterone test might be right for you, check out this comprehensive guide.

How we evaluate home health products and services

At Innerbody Research, we customize our evaluation criteria depending on the type and nature of the health-related service or product. For health products and services, we have five areas that we use for our evaluations, including:

Quality: How well does the company deliver its core service(s) to the customer? For testing services, does the company adhere to the latest and most advanced testing technologies and achieve a very high degree of accuracy? For non-testing telehealth services, is the quality of the service high enough that we would recommend it to loved ones without hesitation? If not, why not?

User-friendly: How intuitive and user-friendly is the service? Does the device, program, app, or website achieve a good degree of user-friendliness for its customers?

Value: Are you getting your money’s worth? Are there any hidden costs or charges? Does the company offer discounts?

Privacy: If health data is stored, will your data be stored securely? Are payments secure?

Customer support: Particularly in situations where ‘one size fits all’ doesn’t make sense, how well does the company help to make the service ideal for you?

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