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Multi GI 5 Reviews: The right probiotic blend for you?

In a diverse field of probiotics, Multi GI 5 stands out for its particular combination of five proven strains. Our team takes a close look to see if it's a good value.

Last Updated: Mar 30, 2022
Multi GI 5

Probiotic supplements have become increasingly popular in recent years as more people understand their gut bacteria’s incredible power over their overall health. This power extends beyond mere physical wellness; studies link gut bacteria balance with everything from cognitive function to emotional wellbeing.

Multi GI 5 offers a probiotic blend combined with amino acids, extracts, and minerals that support gut health. It also includes a prebiotic to help feed the good bacteria. Our testing team compared Multi GI 5 with several other probiotics we’ve examined through the years to determine whether it’s worth your consideration.

Review Summary


  • Can improve digestion
  • Supports healthy weight management
  • Relieves GI distress
  • Contains BioPerine
  • Gluten-free
  • 90-day money-back guarantee
  • Free shipping on orders over $50


  • Not ideal for low-FODMAP diets
  • A bit on the pricey side
  • Only one flavor option

Bottom line

Multi GI 5 is a well-made probiotic supplement that focuses on strains with a lot of scientific backing. It avoids less expensive strains that could bring down its price, making it more expensive than some competitors. Still, that commitment to quality results in a product that should work well for more customers. Those on a low-FODMAP diet may want to start elsewhere due to Multi GI 5’s inclusion of inulin from chicory root, but it’s suitable for FODMAP-conscious eaters in a maintenance phase.

Our Top Picks

Multi-GI 5

Multi-GI 5 is a probiotic supplement designed to improve gut health, relieve GI distress, and support weight management.

The Multi-GI 5 blend is gluten free and contains a variety of amino acids, extracts, and minerals. Enjoy free shipping on select orders and a 90 day money-back guarantee on all orders.

Reviewed by Innerbody Research
Reviewed by Innerbody Research
Reviewed by Innerbody Research

Why you should trust us

At Innerbody Research, we extensively test each health product we review, including Multi GI 5. Our team has collectively spent hundreds of hours testing and researching supplements like Multi GI 5 to provide an accurate, unbiased analysis of how they stack up, free of marketing jargon and gimmicks.

Over the past two decades, Innerbody Research has helped tens of millions of readers make more informed decisions to live healthier lifestyles. We evaluate the service based on adherence to quality, the latest medical evidence and health standards, and a simple question: would we buy the product or service ourselves if it weren’t part of our job, and would we recommend it to family and friends?

Additionally, like all health-related content on this website, this review was thoroughly vetted by one or more members of our Medical Review Board for accuracy.

What is Multi GI 5?

Multi GI 5 is a health and digestive supplement from Unify Health. It combines gut-friendly minerals and amino acids with an effective probiotic blend and prebiotic fiber. It can help populate the gut with good bacteria to improve digestion and nutrient absorption, repair perforations in the intestines, and regulate bowel function.

Unlike many probiotics that come in capsule form, Multi GI 5 is a powder mix you use to create a drink. That makes it easier to take for anyone who has difficulty swallowing pills. It comes in a tasty strawberry lemonade flavor, but that’s the only option.

Who needs Multi GI 5?

Anyone can stand to benefit from a probiotic regimen, and Multi GI 5 offers as good a blend as any. You should consider adding probiotics to your routine if you suffer from any of the following symptoms:

  • Digestive discomfort
  • Bloating
  • Gas
  • Diarrhea or constipation
  • Mood disorders
  • Low energy
  • Problems with weight control
  • Poor sleep

While that may seem like a lot of potential symptoms to be connected with gut health, it’s only a small part of the picture. Of course, there can be any number of causes for physical or emotional distress, so we encourage you to talk to your doctor before introducing probiotics as a potential treatment.

How Multi GI 5 works

Multi GI 5 works by introducing a gut-healthy blend of ingredients to your system, including both probiotics and prebiotic fiber to feed those good bacteria. Their ingredients fall into three categories that we’ll break down for you here.

Gut Health Blend (433 mg)

It appears as though Unify health developed the Gut Health Blend in Multi GI 5 to support the function of the Probiotic Blend. Its ingredients reduce inflammation and digestive discomfort while creating an environment where probiotics can thrive.

Fermented L-Glutamine

Several studies show that glutamine can alleviate IBS symptoms at relatively low doses. It’s potent in conjunction with a low-FODMAP diet, with reductions in IBS severity in as much as 88% of trial participants.

Zinc-Carnosine Complex

Most research into zinc’s role in the gut is limited to animal models using rats or pigs. Some human trials correlate an increase in beneficial bacteria and a decrease in diarrhea-causing microbes with zinc supplementation.

Magnesium Beta-Hydroxybutyrate

Beta-hydroxybutyrate (BHB) comes in several forms, and it’s often connected with gut health among keto dieters. Magnesium BHB may reduce inflammation, which can increase digestive comfort.

Deglycyrrhizinated Licorice Root Extract (<1% Glycyrrhizic Acids)

Gut health is inextricably tied to your immune system, and licorice root appears to have antimicrobial and antiviral properties. That’s thanks largely to its more than 20 triterpenoids and nearly 300 flavonoids.

Black Pepper Extract (fruit)

Supplement companies often include black pepper extract in their products because it can increase the bioavailability of the supplement’s other ingredients. That means your body should absorb more of what a supplement offers when black pepper is present.

Berberine Hydrochloride

While studies into this ingredient are still limited, the research that exists connects berberine hydrochloride with a reduction in gut inflammation. It may also help repair intestinal structures in treating what’s commonly known as “leaky gut.”

Probiotic blend

Each probiotic in Multi GI 5 has a role to play. While one works to aid in weight management, another reduces inflammation. A specific strain can alleviate symptoms like diarrhea or constipation while another regulates immune function. Taken together, this probiotic blend addresses nearly everything that gut health experts say can improve with the right microbial balance.

Lactobacillus gasseri

This strain performs consistently well in mice studies looking at weight management. It regularly reduces body weight and seems to prevent the creation of new fatty tissue. Gasseri may offer significant benefits to premenstrual women. In one study, women reported better mood and less water retention in the days preceding their period.

Bacillus coagulans

This probiotic strain has been tested in constipation-predominant and diarrhea-predominant IBS trials, and it provided decreased symptoms and increased quality of life in both instances. It was well-tolerated in both studies.

Lactobacillus casei

In a study designed to examine the effect of lactobacillus casei on obesity in children, participants saw a significant decrease in body weight (still within healthy loss ranges). Adult trials are not terribly common, but one study looking at this strain as an intervention for diarrhea saw positive results.

Lactobacillus plantarum

A meta-analysis of lactobacillus Plantarum studies reveals that this probiotic can inhibit the immune system’s reactivity to allergens. It can reduce incidences of contact dermatitis and adverse reactions to dust. It can simultaneously enhance the function of anti-inflammatory immune factors and help maintain immune homeostasis.

Prebiotic fiber (37.64 mg)

Prebiotics exist to feed probiotics. They’re fibrous and indigestible by the acid in a human stomach. That allows them to travel to the small intestines, where bacteria can use them as a food source.

What the Multi GI 5 label refers to as a prebiotic blend is a single ingredient: oligosaccharides. These come in the form of inulin the company derives from chicory root. This is where consumers with FODMAP sensitivities need to be careful, as oligosaccharides can contribute to digestive issues.

Is Multi GI 5 safe?

For the most part, Multi GI 5 is perfectly safe. Its probiotics rarely exhibit adverse effects in clinical trials. Its gut health ingredients are similarly safe. As your body gets used to probiotics, you may experience additional discomfort, but this often fades within the first few weeks.

FODMAP concerns

The real safety concern with Multi GI 5 comes from its inclusion of a prebiotic in the form of inulin. By their very nature, most prebiotics pose mild physical dangers to anyone with FODMAP sensitivities.

FODMAP stands for fermentable oligosaccharides, disaccharides, monosaccharides, and polyols. It represents a class of foods that create significant digestive discomfort in certain individuals. These ingredients absorb poorly for most people, but that malabsorption creates bloating, gas, distention, and diarrhea for some.

Not all gut health supplements include prebiotics. Some stick to probiotics alone or probiotics combined with gut health ingredients like the others found in Multi GI 5. If you know you have a FODMAP sensitivity, you may want to look elsewhere for probiotic support.

Some FODMAP elimination diets operate in phases that completely eliminate FODMAPs, then slowly reintegrate them before settling in a maintenance space. One in the maintenance phase, a FODMAP-sensitive individual can consume FODMAPs in moderation and would be a better candidate for a supplement like Multi GI 5.

If you aren’t aware of your food sensitivities, we suggest you take a test that evaluates your sensitivities or your current microbiome level. Innerbody readers have access to exclusive discounts for such at-home tests, and you can find out which are right for you using our guides to food sensitivity testing and microbiome testing.

Pricing and payments

Multi GI 5 is available in 1-, 3-, and 6-month supplies. Larger quantities offer greater savings. Here’s how the price structure breaks down:

  Price Cost per day Total savings
One month $69.95 $2.33 N/A
Three months $188.85 $2.10 $21
Six months $353.70 $1.97 $66

Compared to many other gut health supplements out there, this is a little expensive, even at the six-month tier. Not many supplements combine the quality and balance of ingredients you see in Multi GI 5. It’s a fair value for its potential benefits, but you may be able to find equally effective supplements for less.

Unify Health accepts major credit cards and PayPal.

Shipping from Unify Health costs $4.95 unless you spend more than $50. Orders above $50 receive free shipping, which would apply to any amount of Multi GI 5.

How we evaluate home health products and services

At Innerbody Research, we customize our evaluation criteria depending on the type and nature of the health-related service or product. For health products and services, we have five areas that we use for our evaluations, including:

Quality: How well does the company deliver its core service(s) to the customer? For testing services, does the company adhere to the latest and most advanced testing technologies and achieve a very high degree of accuracy? For non-testing telehealth services, is the quality of the service high enough that we would recommend it to loved ones without hesitation? If not, why not?

User-friendly: How intuitive and user-friendly is the service? Does the device, program, app, or website achieve a good degree of user-friendliness for its customers?

Value: Are you getting your money’s worth? Are there any hidden costs or charges? Does the company offer discounts?

Privacy: If health data is stored, will your data be stored securely? Are payments secure?

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