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Nerve Renew Reviews

We explore Nerve Renew’s vitamin, amino acid, and herbal properties to find out if it can provide real support to your nerves.

Last Updated: Jan 4, 2023
Nerve Renew Review

Our nerves help us understand our physical place in the world. But, like most things, they can malfunction with age. Whether they become oversensitive or fire at random, or if there aren’t enough outside stimuli for your body to understand what’s supposed to hurt, nerve pain can set in. This pain isn’t limited to the elderly and can result from a pinched nerve, viral infections, cancer, untreated diabetes, and more. It’s extremely uncomfortable and can quickly lead to a decreased quality of life.

Nerve Renew is a supplement company that set out to help you minimize potential nerve pain before it begins. They offer a few different product options to pick and choose from, but is that enough? Are their ingredients likely to work, or are they a distraction? We investigated Nerve Renew to help you get the answers.

Review Summary


  • Bioavailable ingredients more likely to be absorbed
  • Supports healthy nerve development and maintenance
  • Made in GMP-certified facilities
  • Third-party tested
  • One-year money-back guarantee
  • Subscribe and save 20%
  • Free shipping on orders over $90
  • Up to 25% off when you sign up for their email newsletter
  • 2 week trial for just $7


  • Can be expensive
  • Third-party testing only occurs once a year
  • Proprietary blend of herbs means it’s harder to tell exactly how much you’re getting

Bottom line

Nerve Renew doesn’t have replacements for nerve pain medication or painkillers, but their supplements offer the right vitamin, mineral, and amino acid mix for your body to strengthen, protect, and support itself. In general, these potent and bioavailable formulas are reasonably priced (except for their titular Nerve Renew) and can help to relieve pain and boost energy long-term. While they aren’t perfect, they’re well-made supplements that are third-party tested and compliant with the latest good manufacturing practices.

Our Top Picks

Nerve Renew

Nerve Renew includes a mix of bioavailable ingredients that promote healthy nerve development and maintenance.

Nerve Renew contains quality ingredients at a fair price. Products are made in a third party, GMP-certified facility. Subscribe to save 20%, or get a 2 week supply for just the price of shipping.

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Why you should trust us

Over the past two decades, Innerbody Research has helped tens of millions of readers make more informed decisions about staying healthy and living healthier lifestyles.

We extensively test each health service or product we review. Our content provides you, our readers, with an unbiased exploration of at-home health options, free of marketing jargon or gimmicks. We evaluate products and services based on their adherence to quality and the latest medical evidence and health standards. We ask ourselves two simple questions: Would we buy the product or service ourselves if it weren’t part of our job? Would we recommend it to family and friends?

Additionally, like all health-related content on this website, this review was thoroughly vetted by one or more members of our Medical Review Board for accuracy.

What is Nerve Renew?

Nerve Renew is a company that’s created and sells several different nerve support supplements. They center around a product also called Nerve Renew that is designed to nourish your nerves, helping them connect with one another and perform routine maintenance. Since your seven trillion nerves send signals to your brain about the external environment and talk to one another, it is essential to ensure that you have enough nutrients to care for them all.

Nerve Renew has a staff physician who helps formulate and approve all supplements. He specializes in family medicine with an emphasis on geriatric care and, as a D.O., has specific knowledge of supplements and herbal remedies. While Nerve Renew’s website seems to focus on nerve pain as a geriatric condition, nerve pain can affect anyone, and their products have no age limit (as long as an adult uses them).

Nerve Renew supplement

Caring for your nerves requires a few strategies, as nerve cells are made from and supported by several different kinds of cells. Nerve Renew’s titular supplement is made from several vitamins to try and tackle it all. Specifically, one serving includes:

Each of these ingredients is used in its most bioavailable form. This allows for maximum absorption, so you get the most benefit from each capsule you take. B complex vitamins, in particular, are extremely well-studied nerve supports, with the most benefits coming from B12 and B6. However, they all work together:

  • B1 gives your nerves energy.
  • B2 is understudied but has some implications in neuroinflammation that can cause pain.
  • B6 regulates neurotransmitter signaling and helps B12 create the myelin sheath.
  • B12 creates myelin, the fatty protective cellular coating that makes up the myelin sheath, which moves information down a neuron.

Be sure that you don’t mix Nerve Renew with another B6 supplement. Taking more than 100mg of vitamin B6 daily can increase your risks of developing peripheral neuropathy and, ultimately, more nerve pain.

Vitamin D, which your body can make but a majority of Americans are deficient in, is an outlier in this formula. Clinical research shows that vitamin D doesn’t directly affect nerve function, but insufficient vitamin D can cause unexplained chronic pain. Adding vitamin D to this regimen covers your bases, ensuring that any pain you might be experiencing from a vitamin deficiency is wiped away.

Stabilized R-alpha lipoic acid looks almost exactly like the alpha lipoic acid that your body makes and uses naturally, making it the easiest for your body to use after you’ve taken it. Like vitamin D, R-alpha lipoic acid doesn’t have obvious links to nerve support. However, studies have shown that it may help lower blood sugar levels. Its antioxidant effects appear to help people with diabetic peripheral neuropathy and autonomic neuropathy, which both cause nerve pain.

One bottle costs $69, which is on the high end for a nerve support supplement. However, you can also order three bottles at a time for $147 (saving $60, bringing you close to a “buy two, get one free” deal), or you can join their subscription program to save 20% on every monthly shipment.

Other Nerve Renew supplements

Nerve Renew capsules aren’t the only thing offered by this company.

Nerve Renew Cream ($27/one bottle, $63/three bottles)

A cream version of the Nerve Renew capsule supplement so that you can target specific areas of pain if you aren’t interested in holistic treatment. Each bottle contains 2.2fl oz of cream, and there aren’t any serving sizes listed as the size of the area that needs cream will vary between individuals.

Nerve Renew Optimizer ($29/one bottle, $69/three bottles)

This is a supplement exclusively made of R-alpha lipoic acid. This potent antioxidant is significantly easier for the body to absorb than other forms of alpha-lipoic acid, and some studies have shown that it may reduce nerve pain. However, most of these studies have been run by one of the major alpha-lipoic acid manufacturers, so take the results with a grain of salt. Each capsule contains 300mg of R-alpha lipoic acid, with 30 servings per bottle.

Total Nerve Care Bundle ($99)

A bundle containing Nerve Renew Cream, Nerve Renew capsules, and Nerve Renew Optimizer, saving you $26 from purchasing them separately.

Optimizer + Cream Bundle ($42)

A bundle containing Nerve Renew Optimizer and Nerve Renew Cream, saving $14.

NO2 Optimizer ($37/one bottle, $87/three bottles)

This nitric oxide supplement is designed to give your body the necessary nutrients to create more nitric oxide. Specifically, it uses four forms of L-arginine — one of the more popular ingredients in nitric oxide supplements — and an amino acid that has implications for circulatory diseases, fatigue, and the immune system. There are 30 servings per bottle with two capsules in a serving.

Curcumin Nerve Defense ($29/one bottle, $69/three bottles)

Curcumin is an anti-inflammatory polyphenol and the main active ingredient in turmeric. This 500mg formula uses the type of curcumin most commonly used in clinical studies, but the body doesn’t absorb curcumin on its own. Instead, it also includes 10mg of black pepper, which increases bioavailability by up to 2,000%. While it won’t perform the full range of support like Nerve Renew, it can still help to manage inflammation and soreness. Each bottle has 30 one-capsule servings.

Sleep Aid ($29/one bottle, $69/three bottles)

In a bit of a side-step from their other formulas, Nerve Renew also offers a supplement with a blend of twelve different vitamins, amino acids, and herbs known to help you relax and sleep easier. This includes everything from vitamin B6 and magnesium to L-theanine and GABA to lemon balm and chamomile. However, it doesn’t contain melatonin or sedatives, promoting natural relaxation. One bottle contains 30 one-capsule servings.

Energy Optimizer ($47/one bottle, $111/three bottles)

This powder contains amino acids, herbs, and traditional teas like green tea and yerba mate, which are full of energizing properties. While there’s about 50mg of caffeine per serving (half of a cup of coffee), Energy Optimizer doesn’t rely on it to give you energy. Instead, it boosts energy by helping your body pick up on NADH production, which boosts energy on a cellular level and may stave off some signs of aging. Mix one scoop with water or juice — Nerve Renew suggests orange or citrus juice for the best flavor — once a day, and this container will last 30 days.


If you know you’ll need a little bit of extra support outside of a Nerve Renew supplement, they’ve still got your back. They sell three different nerve-supporting accessories.

Pack of three copper compression socks ($27)

These knee-high black and gold socks are designed to apply compression to your leg and feet, increasing circulation and reducing swelling, and multiple studies have proven that compression socks work. While copper can help to keep your feet from smelling, there isn’t any evidence that adding copper ions to the fabric increases its ability to compress or prevent fatigue. Available in sizes S/M and L/XL to fit your legs perfectly.

AirTech Circulation Massager ($189)

This massager comes in the form of a pair of knee-high boots that are velcro-wrapped around your legs. Both boots have air pressure pumps attached, so you’ll receive a massage from air pressure variation. Much like a traditional massage, these boot massagers help to relax the muscles and stimulate blood flow through the legs and feet.

Nerve Restore Red Light Slipper ($150)

A single slipper with red and near-infrared light panels containing 132 individual lights on the sole. It may sound like a snake oil accessory, but near-infrared light has shown to both support nerve regeneration and minimize pain from hypersensitivity. The lights are tuned to the same frequencies used in studies, so you can rest assured that your new house slipper can help relieve pain too.

Is Nerve Renew safe?

Generally, yes. Since most of Nerve Renew’s products are made from vitamins, there aren’t many situations where it would be dangerous to take Nerve Renew. However, some medications interact poorly with Nerve Renew’s products. These include:

  • Tetracycline antibiotics
  • Classical (MAOI and tricyclic) antidepressants
  • Levodopa
  • Barbiturates and benzodiazepines
  • Insomnia medications like zolpidem (Ambien) and zaleplon (Sonata)
  • Chemotherapy medications
  • Anti-seizure medication
  • Blood thinners
  • Aspirin
  • Alcohol

The form of vitamin D that Nerve Renew uses (cholecalciferol) is almost always created from animal products, so Nerve Renew may not be the best option if you follow a vegetarian or vegan diet. Be careful if you have diabetes and currently take medication to lower your blood sugar, as Nerve Renew has the potential to lower your blood sugar further.

Children shouldn’t take Nerve Renew. Neither should people who are pregnant or lactating. And, like with all supplements, you should check with your doctor before starting Nerve Renew.

Payments and shipping

Nerve Renew offers free shipping on all overs over $90. Orders that don’t quite hit that mark will be charged $4.97 for shipping. If you live outside of the U.S., you can still order Nerve Renew, but shipping costs vary depending on the package’s weight.

You can use any major credit card for your purchase, but Nerve Renew doesn’t accept any alternative forms of payment.

Subscribe and save

Nerve Renew offers a 20% discount on all of their products if you join their subscription service. They will send you a new bottle of Nerve Renew (or any other supplement they offer) monthly through Recharge, a common, third-party subscription service. There’s no need to make an account when you start a new subscription, but not having an account makes canceling your subscription a little bit more of a hassle — you’ll need to call or email customer support to cancel or modify your subscription when you’re ready.

You can skip, modify, or cancel your subscription at any point. Shipping is free for subscriptions.


It’s easy to save some extra money with Nerve Renew’s rewards program. Once you sign up (which is free), every dollar you spend catalogs one point into your account. You can exchange these points for cashback. Other ways you can earn points include:

  • Making your account (50 points)
  • Leaving a review (100 points)
  • Sharing on Facebook (50 points)
  • Following on Facebook (25 points)
  • Reading About Us page (25 points)

You’ll also receive 200 points on your birthday as a thank-you for being a customer. Plus, if you have friends with nerve pain (or who are trying to avoid developing it in the first place), you can send them a referral link through Nerve Renew’s refer-a-friend program. That link gives them a coupon for $25 off their first order of $50 or more. When they use it, Nerve Renew sends $25 (500 points) directly to your rewards program account.

Every 100 points gives you $5 back. This isn’t a fantastic exchange rate, but it’s better than some other big-name supplement manufacturers. You can get cash back at the following rates:

  • $10 (200 points)
  • $25 (500 points)
  • $50 (1,000 points)
  • $70 (1,400 points)


Nerve Renew offers a long and luxurious return program. They are so confident in their formulas that you have a full year to try their products. If you decide that Nerve Renew isn’t for you at any point in the 365 days after ordering your bottle, you can reach out to customer support and receive a full refund (minus the shipping cost).

They will only refund your most recent purchase; anything you’ve tried and then ordered again is invalid. Any remaining product must be shipped back to Nerve Renew’s refunds department.

Is Nerve Renew a good value?

We think that Nerve Renew is a decent value. As a product, it’s a little expensive, but it provides genuine research-backed support that can make a big difference. On average, competing nerve support supplements cost between $23 and $49 but can drop as low as $13. Even if you use a subscription, you’ll still be paying more than average for this product. However, our testers found genuine relief with Nerve Renew. Its hefty dose of bioavailable vitamin B12 significantly affected the number of times they felt spontaneous painful pins and needles daily.

The rest of their products use the same biomedical framework as Nerve Renew supplements but cost significantly less. The topical Nerve Renew cream, in particular, may be an excellent value if you only experience nerve pain in one part of your body.

Customer support

There are several ways to get in touch with some help, whether to get batch information about your supplement or cancel your monthly subscription. You can:

  • Call (Monday-Friday 7 a.m. to 7 p.m. and Saturdays 9 a.m. to 5 p.m. MST)
  • Email directly
  • Fill out a contact form, which will reroute a response to your email

Nerve Renew also provides their mailing address, but sending an email or placing a call will always be faster unless you’re returning a product. Typically, Nerve Renew’s customer service team gets back to you within 24 hours, but it’s often faster (particularly if you reach out on a weekday). As a nice bonus, Nerve Renew provides a headshot, name, title, and short biography on each customer service team member, so you know exactly who you’re talking to.

How we evaluate health products and services

At Innerbody Research, we customize our evaluation criteria depending on the type and nature of the health-related service or product. In general, we have five broad evaluation areas, including:

Quality: How well does the company deliver its core service(s) or product(s)? How is advanced technology used for accuracy and safety? What evidence of efficacy does the company provide? Are manufacturing standards high-quality?

User-friendly: How intuitive and convenient is the service or product? To what degree is the company interface helpful and understandable?

Value: Are you getting your money’s worth? Are there any hidden costs or charges? Does the company offer discounts?

Privacy: If health data is stored, is it stored securely? Are payments secure? Does the company market your information?

Customer support: With personalized products and services, how well does the company address your individual needs? If a product or service turns out not to work for you, are there satisfaction guarantees or return policies that protect you?

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