mycontentbreak The submandibular gland is one of the three major sets of salivary glands. It is located inferiorly to the mandible or jawbone midway along the inner side of the jaw. It has a muscular covering and empties its contents by way of the submandibular duct into the floor of the mouth on both sides. The sublingual gland, as its name implies, lies under the floor of the mouth and on the side of the tongue.