Wall of the Uterus

The wall of the uterus is relatively thick and is composed of three layers: endometrium, myometrium, and perimetrium. The "endometrium" is the inner mucosal layer lining and is covered with columnar epithelium (tissue that covers all free body surfaces) and tubular glands. The "myometrium" is a very thick, muscular layer, consisting largely of bundles of smooth muscle fibers arranged in longitudinal, circular, and spiral patterns, and interlaced with connective tissue. The "perimetrium" is the outer layer. It is composed of the peritoneal layer of the broad ligament (proper ovarian ligament) that covers the body of the uterus and part of the cervix.