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Best Biotin Supplement

Find out which biotin supplement from our top six picks could help your body break down the nutrients it’s already getting.

Last Updated: Dec 23, 2022
Best Biotin Supplement

Biotin is making waves as a trendy vitamin that’s supposed to help volumize your hair, soften your skin, and grow healthy nails. In a society obsessed with beauty — particularly in the age of Photoshop and face filters — anything that can help you look and feel more beautiful is of top priority. In an effort to keep up with these standards and the popular ideas of what biotin can do for you, some biotin supplements contain up to 100mg of the vitamin. But so many products designed to make you look and feel better are nothing more than sugar pills. Does biotin live up to expectations, or does it fall short?

To investigate whether or not biotin can actually help your body feel its best, we scoured the field and came back with the six best biotin supplements of 2023. We based our decisions on clinical studies, ingredient blends, safety profiles, value, and more.

If you’re in a hurry, check out our top picks below.

Summary of recommendations

Our Top Picks

HUM Nutrition Killer Nails

HUM Nutrition Killer Nails’ streamlined ingredient profile is scientifically backed and effective. It’s the perfect solution for dry and brittle nails.

HUM Nutrition is a vegan friendly solution that contains 5,000mcg of pure biotin. Their products are backed by numerous clinical studies and independently triple-tested by third parties. Save up to 50% on your first order.

Top considerations for a biotin supplement


Winner: Life Extension

The cost of a supplement is one of the first things we consider when comparing options. A high-cost supplement that provides the same ingredients at the same — or lower — quality than another isn’t always a good option. Still, subscription programs, bulk deals, and customer service policies like money-back guarantees might make a supplement worth it. Serving size and the number of servings per container also make a difference in a supplement’s overall value.

Not only does Life Extension give you more than three months’ worth of biotin supplements for the price of a flavored venti latte, but they are made well with one high-quality ingredient and robust customer service. You can enroll in Life Extension’s AutoShip & Save program to save another 13%, bringing your total price down to $5.25 for 100 tablets. They might not be the most powerful tablets on the market, but each 600mcg serving is still 200 times the adequate biotin intake. Life Extension’s one-year money-back guarantee ensures that you have the flexibility to change your mind.


Winner: Vegamour

Some biotin supplements provide just biotin. Those are great, particularly if you’re looking to heal a general deficiency rather than capitalize on one of biotin’s many effects. However, not everyone interested in biotin supplements wants the same broad range of benefits. Biotin supplements often have other vitamins, minerals, and herbs added individually or in proprietary blends to home in on and sharpen the focus on hair, nail, or skin health. No matter the ingredients, it’s also essential to ensure that all components are high-quality, well-sourced, and appropriately dosed for the issue.

Vegamour is the only company on our list that makes a biotin supplement with other ingredients but doesn’t hide any quantities in a proprietary blend. The supplement facts list everything in the GRO Biotin Gummies, sparing no details. Almost every ingredient is included in clinically effective quantities (except for inositol, which is studied in doses closer to 1g for hair loss). And while it needs extra ingredients like sugar, tapioca syrup, and citric acid as a gummy, the vegan, gluten-free formula doesn’t use any artificial flavors, allergens (aside from soy), or GMO products.


Winner: HUM Nutrition

Biotin has been well-studied as a vitamin, and what it can and can’t do is relatively well-established. Supplements that don’t make grand claims outside of biotin’s range of influence are more likely to give you reasonable expectations and are more likely to prove to you that they understand what they’re creating (and what you’re putting in your body). Biotin supplements that are tested in clinical studies, or that are clearly inspired by clinical research, are most likely to score well in our efficacy category.

HUM Nutrition’s Killer Nails only contains vegan biotin. They point to a scientific study to explain exactly why the pure biotin formula is marketed specifically toward nail health, as well as why they picked their relatively high dosage. Not only do they reference this scientifically-sound study, but they include a direct link on Killer Nails’ webpage so you can decide for yourself. Plus, they discourage excessive biotin use that other companies provide readily in one serving. HUM Nutrition recommends in their FAQ that you don’t combine Killer Nails with other biotin-based supplements to avoid breakouts and false negatives on important health tests (which we’ll discuss in detail later).


Winner: HUM Nutrition

Safety is one of the most important factors when it comes to finding the right supplement. All of our top six supplements are well-tested using high-quality manufacturing facilities. We specifically chose biotin supplements that have 5,000mcg or less, as the FDA has issued warnings that biotin supplements that contain too much (estimated by researchers to be about 10,000mcg) can cause false negatives on tests for things like thyroid disorders and heart attacks. A supplement should help, not hurt, your chances of feeling better.

HUM Nutrition’s Killer Nails supplement contains 5,000mcg of biotin, brushing up against the upper limit on our requirements. Still, they are aware of the dangers of going beyond that, unlike some other supplement manufacturers. They outright recommend not combining Killer Nails with other supplements that contain biotin to avoid any risks of acne or incorrect test results. They triple-check their formulas for quality and potency using both in-house and independent third-party testing, and all manufacturing facilities are GMP-certified and FDA-registered.


Winner: Life Extension

A supplement’s convenience is an easy way to tell whether or not you’ll use it. Supplements with complicated time schedules or multiple capsules, or ones that require you to re-order packages regularly might become a chore — sometimes enough to abandon the routine, keeping you from their benefits.

Life Extension simplifies the ordering process and actual supplementation for their biotin supplement. Each bottle contains 100 capsules, and you’ll take only one per day (at any time, with or without food), so one bottle will last you more than three months. Their AutoShip & Save program has tons of flexibility, too: you can order anywhere from one to ten bottles at intervals ranging from once a month to once a year. This level of personalization ensures you can get exactly how much biotin you need at your convenience.

How our top recommendations compare

It can be confusing to balance intricate details about multiple supplements at once. To help you understand the benefits and drawbacks of each of our top picks, we’ve put together a chart that covers the most essential elements of each below.

  HUM Nutrition Life Extension Nutrafol Vegamour Primal Harvest Vital Proteins
Cost $10 $6 $79 $28 $28 $30
Number of servings 30 100 30 30 30 30
Cost per serving $0.30 $0.06 $2.63 $0.93 $0.93 $1
Serving size 1 capsule 1 capsule 2 capsules 2 capsules 2 capsules 2 capsules
Biotin content 5,000mcg 600mcg 3,000mcg 5,000mcg 4,000mcg 150mcg
Other active ingredients     Vitamin A, C, D, iodine, zinc, selenium, Synergen Complex, Nutrafol Blend Vitamin A, B5, B6, B9, B12, C, D3, E, choline, zinc, iodine, inositol Vitamin B3, B5, B6, C, calcium, zinc, copper, silicon, horsetail extract Vitamin B1, B2, B5, B6, B9, C, E, selenium, silica
Subscription available
Return policy 30 days 365 days 30 days 90 days 90 days 30 days

What is biotin?

Biotin, or vitamin B7, is an essential vitamin once known as vitamin H. It helps your body break down carbohydrates, protein, and fats and turn them into energy. While it’s most famous as a supplement that improves your hair, nails, and skin, it also regulates gene expression and the nervous system, as well as adrenal, thyroid, and pancreatic functioning.

As an essential vitamin, our bodies can’t create biotin on their own. Instead, we need to get it from food. Unlike most essential vitamins, however, the microflora in our intestines can sometimes synthesize biotin. These organisms have a symbiotic relationship with biotin; not ingesting enough can lead to microbial imbalances (also known as gut dysbiosis) and Lactobacillus murinus overgrowth. Overgrowth can ironically speed up hair loss and, in some cases, even induce it.

Biotin is also a water-soluble vitamin. It can be fully absorbed into water, and when there’s too much for our bodies to use, it gets excreted through our urine, making it harder for adverse side effects from biotin build-up.

How much biotin you should get per day depends on your age. While there isn’t a set daily required intake, the National Institutes of Health recommend the following doses:

  Dose Dose (Pregnant) Dose (Lactating)
0-6 months 5mcg    
7-12 months 6mcg    
1-3 years 8mcg    
4-8 years 12mcg    
9-13 years 30mcg    
14-18 years 25mcg 30mcg 35mcg
19+ years 30mcg 30mcg 35mcg

Most people get more than enough biotin through their diets alone. The average American eats between 35mcg and 70mcg of biotin a day through foods like:

  • Eggs
  • Animal liver
  • Salmon
  • Pork
  • Beef
  • Sunflower seeds
  • Sweet potatoes
  • Almonds
  • Tuna
  • Spinach
  • Broccoli
  • Cheese
  • Milk
  • Yogurt
  • Oatmeal
  • Banana

Eggs are a particularly good source of biotin, containing 10mcg per egg. However, they need to be cooked: raw egg whites contain avidin, a protein that binds to biotin and prevents your body from getting any of the nutrient. In excess, too many raw egg whites can even cause a biotin deficiency.

Biotin deficiencies are rare, mostly occurring in pregnant and lactating people. Those who can’t absorb nutrients or use a feeding tube or other form of parenteral nutrition are at a higher risk of developing a biotin deficiency. So are people on antiepileptic, isotretinoin, and antibiotic medications. A biotin deficiency might look like:

  • Hair loss
  • Scaly red rash around mucus membranes (eyes, nose, mouth, genitals)
  • Unusual facial fat distribution
  • Depression
  • Lethargy
  • Hallucinations
  • Numbness and tingling
  • Seizures

How do biotin supplements work?

Biotin supplements add biotin to your daily intake, just like biotin-rich food but in higher concentrations. Research has shown that biotin can improve brittle nails’ firmness and thickness. And it helps to keep zinc levels at an average in your skin, developing protein, healing wounds, and acting as an antioxidant for the largest organ in your body.

Studies on biotin’s effects on hair growth are mixed. Biotin alone doesn’t affect hair loss in clinical studies, but it increases your body’s keratin levels. Essentially, biotin doesn’t change the hair follicle itself, but it gives the body more protein to make strong hair. Your body may or may not need more keratin to produce more hair or improve its thickness, so a biotin supplement might not change your hair. However, some people anecdotally find great success with biotin supplements.

Wanting more hair growth is an incredibly common reason people turn to supplements. It’s the reason that people will also use medications like minoxidil and finasteride or alternative treatments like laser caps and shampoos. Biotin supplements may cater to those seeking more hair growth and will include a blend of other ingredients designed to improve multiple situations that could cause weak, damaged, or thinning hair. Both biotin-only and blended supplements have their pros and cons. We’ve included both on this list to give you the broadest range of options.

A biotin supplement might also include:

  • Other essential vitamins (especially A, B1, B2, B3, B5, B6, B12, C, and D)
  • Choline, which also affects gene expression and lipid metabolism
  • Zinc, which also affects DNA synthesis, enzymatic activity, and wound healing
  • Iodine, which is important for thyroid health
  • Selenium, which affects the thyroid, DNA synthesis, and oxidative damage

Blends might also include herbs like saw palmetto for men’s hair loss, inositol to prevent hair loss from endocrine disorders like polycystic ovarian syndrome (PCOS), and horsetail extract, which has large amounts of silica.

Biotin supplement safety

It’s easy to get too much biotin. This isn’t generally a health concern, as biotin is water-soluble and will flush itself out of your body in excess through your urine. However, in 2017, the FDA wrote some safety recommendations about biotin supplementation’s negative effects. Excess biotin supplementation can impact the measurements of several kinds of critical health tests, including:

Cardiac tests

Myoglobin, creatinine kinase, cardiac troponin I, high sensitivity troponin T (hs-TnT)

Endocrine tests

Thyroid stimulating hormone (TSH), triiodothyronine (T3), thyroxine (T4), antibodies fighting thyroid peroxidase (anti-TPO), antibodies fighting thyroglobulin (anti-TG), C-peptide, insulin, ACTH, cortisol

Cancer screening tests

Ca125 (ovarian cancer screening), Ca15-3 (breast cancer metastasizing into bone), CA 19-9 (pancreatic cancer), prostate-specific antigen (PSA, a marker for prostate cancer)

Sex hormone tests

Estradiol, progesterone, prolactin, follicle stimulating hormone (FSH), lutenizing hormone (LH), testosterone, DHEAS (the precursor to testosterone), sex hormone binding globulin (SHBG)

Pregnancy and fetal health tests

Alpha-fetoprotein (AFP), carcinoembryonic antigen (CEA, a protein released by fetuses that also allows doctors to monitor cancer treatment), beta-hCG (beta-human chorionic gonadotropin)

Other tests

Vitamin B12, vitamin B9 (folate), Immunoglobulin E (IgE)

Taking too much biotin might increase or decrease these numbers, resulting in false positives (primarily for thyroid disease) and false negatives. This means that a biotin supplement that is too strong might hide the fact that you’ve just had a heart attack, resulting in delayed care or worse.

What consists of “too much” biotin hasn’t been consistently pinned down. Some studies have marked the cutoff at 10mg of biotin daily, but others reveal that how much is in your blood makes a bigger difference than how much you take. Considering that some biotin supplements can have up to 100mg per serving, it’s best to always read the facts before starting a new supplement, especially if you have diabetes, have heart or thyroid problems, or are at a higher risk of cancer.

Taking too much biotin can also lead to cystic acne breakouts, a type of painful inflamed acne. For some people, taking any biotin can cause it. While there’s little-to-no research that explains why this happens to people, one theory is that taking biotin can offset or suppress vitamin B5 levels. Vitamin B5 helps the body quiet unruly stress hormones and maintain skin health, among other things. One study found that adding a vitamin B5 supplement improved acne more than a placebo over 12 weeks. However, this theory is still unproven. The first signs of cystic acne typically appear within three weeks of starting a biotin supplement, so keep an eye on your skin while you’re getting started.

However, if your doctor prescribes a biotin supplement, you should still take it at the prescribed dose. Some experts recommend taking 100mg to 300mg of biotin daily as part of the treatment plan for multiple sclerosis (MS), though studies have found no observable benefits yet.

Who should avoid biotin?

Biotin is a safe supplement. No side effects are associated with taking biotin, though some people may experience an upset stomach as they acclimate. At this time, there aren’t any known interactions between prescription medications or herbal supplements and biotin, so it’s easy to add to your daily regimen.

People with diabetes should avoid biotin supplements unless given the go-ahead by their doctors. When combined with chromium, biotin can reduce insulin resistance and lower average blood sugar levels. One 2013 study found that taking 40mcg of biotin per kilogram of body weight lowered the average HbA1C in patients with type 1 diabetes. If you’re taking insulin, this might mean that you need less of it or are more likely to combat low blood sugar. Be cautious, and talk to your doctor if you want to try biotin supplementation.

You should also talk to your doctor before starting a biotin supplement if you’re pregnant or breastfeeding. Pregnant people are most likely to have a biotin deficiency (as are those who’ve had bariatric surgery or aren’t able to absorb nutrients through their stomachs), so it’s generally advised to take slightly more biotin. This means 35mcg a day rather than 30mcg, which is the equivalent of adding roughly one cup of sweet potatoes or half of an egg to your day. If you’re interested in trying a biotin supplement, reach out to your doctor to ensure you’re meeting all of your nutritional needs.

Children can take biotin supplements, but it’s not recommended since their daily nutritional needs are low. Talk to their pediatrician if you’re concerned about their hair, nails, or dietary habits. A children’s multivitamin will likely be the best option.

HUM Nutrition Killer Nails

Best overall and best vegan


  • Simple, pure formula
  • Backs all promises up with scientific studies
  • Independently triple-tested by third parties
  • Vegan-friendly
  • Access to a registered dietician with an active subscription
  • Strong sustainability practices
  • Free samples in every box
  • Free shipping over $50
  • Save up to 50% on your first order


  • Only available as a subscription
  • 5,000mcg may be too strong for some

It might be advertised as a nail product, but HUM Nutrition’s Killer Nails has just one ingredient: 5,000mcg pure vegan biotin. This biotin is just as good at caring for your nervous system as it is at improving the quality of your nails.

HUM Nutrition backs up their claims with a clinical study that showed 25% thicker nails over six months in people with brittle, splitting, and soft nails. This is a common trend for their products, as every ingredient they include has clinical sources linked directly on their product pages. And Killer Nails isn’t HUM Nutrition’s only biotin supplement — they also offer Hair Sweet Hair, a vegan gummy with extra ingredients for hair health, and Runway Ready for holistic hair, skin, and nail health. However, HUM Nutrition doesn’t recommend taking either of these with Killer Nails to prevent any potential adverse effects from too much biotin (like acne and inaccurate test results), which is a compassionate step above and beyond what most other biotin manufacturers will tell you.

Killer Nails is made in a GMP-certified facility and is tested three times (at least once by an independent third party) for purity and potency. One container holds 30 capsules, which is enough for 30 days.


HUM Nutrition only provides its supplements using a subscription model. No matter what you order, you’ll automatically get a package delivered once a month. However, HUM Nutrition lets you skip, change dates, and cancel your subscription hassle-free. If you want to try Killer Nails but aren’t sure if you want to commit, you can always cancel your subscription after ordering your first jar. Subscriptions also allow access to HUM Nutrition’s team of registered dieticians, where you can get expert advice on your health.

Each 30-serving container costs $10, and you can save up to 50% on your first order by taking their pairing quiz (which takes less than five minutes and doesn’t lock you into any of their product recommendations). Plus, if you want to try two or more other HUM Nutrition products, you’ll save at least 25% per order with their bundle deal.

Shipping is free on orders over $50 and costs a flat fee of $5.95 for others. If you decide that Killer Nails isn’t the right biotin supplement for you after you order it, you can return it. However, the bottle needs to be unopened to receive a full refund. Opened products can be returned for store credit. You’ll have to pay for return shipping as well.

Life Extension Biotin

Best budget pick


  • Great value
  • 100 servings per bottle
  • Certificate of Analysis proves testing
  • Made in a GMP-certified facility
  • Free shipping on orders over $50
  • Bulk purchases save 13%
  • One-year money-back guarantee
  • Join their AutoShip program to save 13%


  • Contains magnesium stearate and dicalcium phosphate
  • Dose may be a little low for some

Life Extension is a health product company with a vast catalog spanning everything from supplements to lab tests. They even produce their own Life Extension magazine. Yet, Life Extension still prioritizes their supplements. They make every formula with high standards, and their biotin supplement is no exception.

This biotin supplement has 100 capsules per container. Since one capsule is one serving, this bottle will last you more than three months if you take it daily. Each capsule contains 600mcg of pure biotin without any other active ingredients. While that isn’t the highest dose on our list (rather, the second lowest), it still provides 20 times the adequate intake for adults, which is more than enough to improve nutrient breakdown. And since there’s only biotin (and two stabilizers, magnesium stearate and dicalcium phosphate), you don’t have to worry about allergens, GMOs, or artificial colors or flavors.

Life Extension tests all of their supplements and has the Certificates of Analysis available for every product on their website. It isn’t always easy to find — you’ll have to go through their FAQ for more information — but they do make it public, which isn’t the case for many other supplement companies. All supplements are made in GMP-certified facilities, too.


There are three pricing options when you purchase Life Extension’s Biotin supplement. You can buy a container one time for $6, or you can join their AutoShip & Save program to give you the lowest price and automatic free shipping. AutoShip & Save takes 13% off, bringing the cost of each bottle down to $5.25. And if you purchase four or more bottles at a time, you’ll automatically get that 13% discount, whether or not you’re joining the subscription program. Unfortunately, you can’t combine these 13% discounts; subscription orders of four or more bottles get no additional discounts.

AutoShip & Save allows you to pick how often you want to receive your shipment and how many bottles you get at once (up to 10). You can get a new box every:

  • One month
  • Two months
  • Three months
  • Four months
  • Six months
  • Nine months
  • 12 months

If you place a one-time order, shipping is free for orders over $50. Otherwise, it costs $5.50 for standard three- to five-day shipping. You can also join Life Extension’s Premier Rewards program ($49.95 annually) for free shipping on every order, as well as gifts, 4% back on every purchase, a 12-month subscription to their magazine, and more.

Our full review of Life Extension goes into more detail about the Premier Rewards program, Life Extension’s testing policies, the rest of their catalog, and more.

Vegamour GRO Biotin Gummies

Best gummy


  • Tasty natural strawberry flavor
  • Provides 11 other essential vitamins and minerals
  • Vegan formula
  • Tested in-house for purity
  • Produced in a GMP-certified facility
  • Subscribe & save 14%
  • Free shipping on orders over $50


  • Gummy isn’t the best way to take vitamins
  • Not diabetic-friendly
  • Not third-party tested

Vegamour’s focus on healthy beauty doesn’t stop with hair products and topical serums. They produce three supplements, all of which are designed to improve hair quality, thickness, and growth rate. But GRO Biotin Gummies, the cornerstone of Vegamour’s supplements, have a straightforward ingredient list designed to improve most people’s hair. Ingredients include:

  • Vitamin A: 630mcg
  • Vitamin C: 20mg
  • Vitamin D3: 100IU or 10mcg
  • Vitamin B5: 5.2mg
  • Vitamin B6:2mg
  • Vitamin B9: 260mcg
  • Vitamin B12: 6mcg
  • Biotin: 5,000mcg
  • Choline: 40mcg
  • Zinc: 2.7mcg
  • Iodine: 24mcg
  • Inositol: 40mcg

Inositol is an ingredient that’s unique to GRO Biotin Gummies. The sugar was once classified as vitamin B8 but has since been stripped of the title. It provides structure to cells and improves insulin’s performance in the body, stabilizing blood sugar and decreasing insulin resistance. Inositol also helps to balance hormones, which is likely why it’s included in this biotin supplement — hormonal imbalances in women often lead to hair loss. Inositol’s presence means that people with diabetes should be cautious about using this supplement. It might decrease your average blood sugar, making you more likely to go into hypoglycemia while adjusting your insulin levels.

Very few studies look at inositol’s role in hair loss, and those use it in much higher doses. About 1mg of inositol is the average in studies; in contrast, 4-8mg is regularly prescribed for insulin resistance. You can go up to 12-18mg to help treat mental health conditions like panic disorder and obsessive-compulsive disorder. 40mcg might not be enough to affect hair loss.

Because of their gummy form, GRO Biotin Gummies have more ingredients than other biotin supplements. They also include:

  • Tapioca syrup
  • Cane sugar
  • Dextrose (a simple sugar chemically identical to glucose)
  • MCT oil

Gummy vitamins aren’t always the best way to get nutrients. They often denature during the gummy creation process and are harder for your body to break down, meaning you’ll ultimately get less than is stated in the supplement facts. That said, sometimes gummies are the only way a person can handle a supplement, and some nutritional boost is better than none.

One serving is one heart-shaped, strawberry-flavored gummy per day. Their strawberry flavor is mild and sweet, as it’s been made with natural ingredients rather than artificial flavoring, and they’ve been rolled in citric acid to help their flavor pop.

GRO Biotin Gummies aren’t third-party tested (only GRO+ Advanced, a version of GRO Biotin Gummies with added CBD oil, are). However, they are tested in-house for purity. All gummies are manufactured in GMP-compliant facilities. Vegamour states that you might find success within a few months of use, but most reviewers found their hair notably thicker after one year of consistent use.


One jar of GRO Biotin Gummies costs $28. However, you can join Vegamour’s Subscribe & Save program to save $4 (14%). The subscription program automatically ships you a new jar once a month, but you can skip or cancel your subscription anytime without penalty.

Vegamour offers free shipping on all orders over $50 or a flat rate of $5 for all other orders anywhere in the United States. They also have a 90-day money-back guarantee, so you can return anything you’ve tried and don’t like within 90 days of purchase, but be aware that there’s a $5 handling fee for all returns. You’ll have to pay return shipping, too.

If you’re interested in learning more about Vegamour, check out our full review.

Nutrafol Proactive Thinning

Best for men


  • Standardized formula ensures equality in every capsule
  • Ingredients backed by clinical research
  • Made in cGMP-certified FDA-registered facilities
  • Free doctor consults with subscription program
  • Subscribe & save up to 20%
  • Free shipping to the U.S.


  • Proprietary blends obscure ingredient amounts
  • Not budget-friendly
  • Contains fish
  • Four capsules per day in a serving

Nutrafol makes mostly biotin-based supplements designed to support hair growth. These supplements are divided into women’s care (Women, Women’s Balance, and Postpartum) and men’s care (Proactive Thinning and Hairline Defender). We think that Proactive Thinning, their cornerstone men’s product, is the best biotin supplement for men. Their women’s products are also excellent, but when two-thirds of men note hair loss by 35 (and 85% do by 50), men need a little extra help in this setting. And while this supplement has excellent potential as a hair loss remedy, its male-centric ingredients mean women can’t take it, and women still make up about 40% of people with hair loss.

Proactive Thinning is a daily biotin supplement that improves hair growth and thickness by addressing hormonal imbalances, stress, and poor nutrition with a biotin backbone. Every four-capsule serving includes:

  • Vitamin A: 5,000IU or 1,563mg
  • Vitamin C: 60mg
  • Vitamin D: 2,500IU or 62.5mg
  • Biotin: 3,000mcg
  • Iodine: 225mcg
  • Zinc: 25mg
  • Selenium: 200mcg
  • Synergen Complex: 1,720mg
  • Nutrafol Blend: 575mg

Synergen Complex and Nutrafol Blend are both proprietary blends, meaning that while they list the ingredients (many of which are well-researched and have strong clinical support), it’s unclear how much of each is in the formula. This makes it especially difficult to pin down whether or not there’s enough for each ingredient to be effective. That said, the Synergen Complex contains the following:

The Nutrafol Blend is made of:

The blend combines anti-inflammatory, antioxidant, and amino acid ingredients to improve hair growth from its initial growth stages onward. Nutrafol promises results in three to six months. And while they don’t link to or cite any studies directly on the webpage for Proactive Thinning, they do state that all ingredients are clinically effective.

All Nutrafol products are manufactured in FDA-registered and cGMP-compliant facilities.


You can order Nutrafol’s Proactive Thinning supplement in a few different ways. You can purchase one bottle one time for $88. Or, you can join their subscription program, which allows you to order recurring deliveries of bottles in the following sizes:

  • One bottle (one-month delivery): $79
  • Three bottles (three-month delivery): $224
  • Six bottles (six-month delivery): $422

You can pause, skip, or cancel your subscription at any time. Subscriptions also unlock access to Nutrafol’s naturopathic doctor, so you can get professional guidance while using their supplements.

All deliveries — subscription or non — have free shipping if you’re in the United States. Nutrafol can only ship to a small handful of countries outside the U.S., so contacting customer service is necessary to start an international order.

Nutrafol offers a 30-day return policy, so if you aren’t happy with what you’ve ordered, you can exchange it within 30 days of purchase. It has to be in the same condition as you received it and in original packaging for a full refund.

Want to learn more about everything Nutrafol has to offer? Check out our full review.

Primal Harvest Hair Growth Complex

Best for hair loss


  • Robust biotin content
  • Small but powerful ingredients list
  • Supports hair, scalp, and overall health
  • Made in GMP-certified facilities
  • Orders ship same-day
  • Free shipping on orders of $75 or more
  • Subscribe and save up to 18%


  • Horsetail extract contains small amounts of nicotine
  • Not many studies proving silicon’s effectiveness

Adding biotin is one step that can improve your hair’s health, but more things could cause thin, dull, or sparse hair than just a keratin or biotin deficiency. Your scalp might be creating an unhealthy environment for hair growth, or you might be experiencing less circulation than you used to. Primal Harvest takes a holistic approach to their Hair Growth Complex, covering all the bases necessary for all-around hair health.

One two-capsule serving of Hair Growth Complex includes:

  • Biotin: 4,000mcg
  • Vitamin C: 200mg
  • Vitamin B3: 30mg
  • Vitamin B5: 15mg
  • Vitamin B6: 2mg
  • Calcium: 35mg
  • Zinc: 20mg
  • Copper: 1.6mg
  • Horsetail extract (7% silica): 25mg
  • Silicon: 3mg

The inclusion of horsetail extract is unique on our list. The living fossil is a traditional herb whose use dates back to ancient Rome and Greece. It’s currently known to regulate a hair growth cycle, improving cell turnover to ensure a healthy environment. However, horsetail extract does contain small amounts of nicotine, so this supplement isn’t a good idea to share with children or those who’ve quit smoking, vaping, or chewing tobacco.

All Primal Harvest products are made in GMP-certified facilities and are tested by third parties for quality, purity, and potency.


Primal Harvest sells their Hair Growth complex in sets of one, two, three, or four bottles. You can order them as a one-off purchase or join their subscription program for automatic free shipping and additional savings.

Primal Harvest lists the prices for Hair Growth Complex according to how much you’ll pay per bottle, not per order. All subscription programs cost the same per bottle ($27.84) no matter how many you order at a time, but the numbers vary for one-time purchases. We’ve put together a chart to help you visualize the different prices — and how much you’ll actually pay — below.

  One-time purchase (each) One-time purchase (total) Subscribe & Save (total)
One bottle $33.95 $33.95 $27.84
Two bottles $31.95 $63.90 $55.68
Three bottles $29.95 $89.95 $83.52
Four bottles $27.95 $111.80 $111.36

If you don’t join the subscription program, you still have a chance at free shipping if you spend at least $75 (three or more bottles or one or two bottles with other Primal Harvest products). All orders placed by 3 P.M. on a business day will ship same-day.

Primal Harvest backs all of their products with a 90-day money-back guarantee. If you’re unsatisfied with your Hair Growth Complex, contact customer support through email, in-browser messenger, or phone to get the return process started. Opening and using some supplements doesn’t disqualify you from an order, either — if you’ve purchased one bottle, they’ll provide a full refund as long as you’re within 90 days of purchase. Buying two or more means you’ll only get a full refund for one open bottle (the rest must be unopened).

Our full review of Primal Harvest will give you more detail about their entire catalog, including sales, deals, and their subscription program.

Vital Proteins Beauty Boost

Best beauty blend


  • Combination of vitamins and herbs addresses root causes
  • Plant-based formula
  • Gluten, dairy, and GMO-free
  • Independent third-party tested
  • Made in a cGMP-certified facility
  • Free shipping on orders over $50
  • Subscribe and save up to 25%


  • Large capsules
  • Very small biotin dose

Vital Proteins created several beauty formulas, but their best — Beauty Boost — is easy to take and boasts a clean formula. This biotin-focused supplement contains many other B vitamins and minerals critical for hair, skin, and nail health. Each two-capsule serving of Beauty Boost contains:

  • Biotin: 150mcg
  • Vitamin C: 180mg
  • Vitamin E: 20mg
  • Vitamin B1:
  • Vitamin B2: 3mg
  • Vitamin B3: 5mg
  • Vitamin B5: 5.7mg
  • Vitamin B6: 3.3mg
  • Vitamin B9: 400mcg
  • Selenium: 70mcg
  • Silica: 200mg
  • Organic Beauty Blend: 1.4g

The Organic Beauty Blend includes a long list of organic herbs and natural extracts, such as:

  • Amla berry extract
  • Bamboo shoot extract
  • Alfalfa leaf
  • Guava extract
  • Holy basil extract
  • Lemon extract
  • Annatto extract
  • Sesbania extract
  • Mustard extract

The blend was designed to encompass more natural forms of vitamin B, making the Beauty Boost formula more robust and adding health benefits for your scalp. That said, 150mcg of biotin is a very small amount compared to other formulas. 150mcg is still 500% of the NIH’s suggested adequate intake for adults, but the comparatively-low dose means there’s a slightly larger chance this formula won’t work for you.

Each bottle contains 30 servings (60 capsules). All Vital Proteins products are tested by independent third parties and are created in cGMP-certified facilities.


Beauty Boost is available as a one-off purchase or as part of Vital Proteins’ subscription service. However, depending on how long you’re part of the Subscribe & Save program, you’ll pay a different amount.

  • One-time purchase: $30
  • Subscription, first order: $22.50 (25% off)
  • Subscription, second order and beyond: $25.50 (15% off)

You can have your subscription delivered every one to eight weeks, but there aren’t any options to push your subscription delivery out more than two months at a time. All subscription orders get free shipping, and changing your delivery date or canceling your subscription is easy to do at any time. If you aren’t joining a subscription, shipping is free for orders over $50. Shipping fees vary for smaller orders depending on where you’re located and what you’re ordering but average about $6 for one container of Beauty Boost.

Vital Proteins offers a 30-day money-back guarantee, so contact customer support to get the return started within 30 days of receiving your supplements. There’s a chance you might be charged a small restocking fee but will otherwise get a full refund.

FAQ about biotin supplements

How long does it take to see results with a biotin supplement?

You likely didn’t lose your hair overnight, so don’t expect it to grow back overnight either. It takes most people 2-4 months to see and feel the results of supplementing biotin. Hair growth cycles can last several years, so some reviewers report biotin supplements taking up to a full year to see a big difference.

Should I take biotin in the morning or at night?

You can take biotin at any time, but most providers recommend taking it in the morning. Digestion slows overnight, so taking it in the morning ensures that it’ll be fully broken down and absorbed while you go about your day.

What are some natural sources of biotin?

Most people get enough biotin from their diet. You can get biotin from:

  • Animal products (meat, fish, eggs, and liver)
  • Seeds
  • Nuts
  • Sweet potatoes
  • Spinach
  • Broccoli
  • Mushrooms
  • Avocados

Eggs are one of the best sources of biotin, as one yolk contains 10mcg, but they need to be cooked since avidin, a protein in raw eggs, binds to biotin and stops your body from absorbing it.

Does biotin influence facial hair growth?

Biotin can affect hair thickness by increasing how much keratin your body makes, but we don’t know whether or not it can affect the thickness of your beard hair. There haven’t been many studies yet on whether or not biotin affects facial hair growth. Based on the fact that biotin has been shown in a few studies to increase hair thickness in people struggling with things like male pattern baldness, it might make an impact on your facial hair, too.

Can biotin be absorbed through the skin?

Some places claim that your hair and skin can absorb biotin as well as your stomach can. This thought process is based on one study from 1999 that hasn’t yet been replicated. Besides that one study, there’s no evidence that biotin is absorbed directly through the skin. If biotin doesn’t reach your stomach and intestines, it’s unlikely that it’s making a difference.

Should I take biotin or a B-complex vitamin?

Biotin is often paired with other B-vitamins like pantothenic acid (B5) and B12. B-complex vitamins contain all eight B-vitamins, giving you the benefits of not only all eight vitamins but their interactions and combined strengths. There’s no harm in taking a B-complex vitamin if you want to bump up your biotin levels (assuming it won’t interact with other medication you take). All B-vitamins are water-soluble; any excess will be excreted through your urine. That said, you might not find any benefits if you’re not deficient in any B-vitamins, and there are some side effects like headache and an upset stomach associated with high doses of some B-vitamins like B12.

Why you should trust us

Over the past two decades, Innerbody Research has helped tens of millions of readers make more informed decisions about staying healthy and living healthier lifestyles.

We extensively test each health service or product we review. Our content provides you, our readers, with an unbiased exploration of at-home health options, free of marketing jargon or gimmicks. We evaluate products and services based on their adherence to quality and the latest medical evidence and health standards. We ask ourselves two simple questions: Would we buy the product or service ourselves if it weren’t part of our job? Would we recommend it to family and friends?

Additionally, like all health-related content on this website, this review was thoroughly vetted by one or more members of our Medical Review Board for accuracy.

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